2-MORPHOLINECARBOXYLIC ACID HCL

Base Information

• Chemical Name: 2-MORPHOLINECARBOXYLIC ACID HCL
• CAS No.: 300582-83-6
• Molecular Formula: C5H9NO3
• Molecular Weight: 131.13000
• Hs Code.: 2934999090
• Mol file: 300582-83-6.mol

Synonyms:2-Morpholinecarboxylicacid;

Chemical Property of 2-MORPHOLINECARBOXYLIC ACID HCL

Chemical Property:

• Boiling Point: 298.538 °C at 760 mmHg
• PKA: 2.57±0.20(Predicted)
• Flash Point: 134.351 °C
• PSA: 58.56000
• Density: 1.24 g/cm³
• LogP: -0.61180
• Storage Temp.: Store at 0°C

Purity/Quality:

97% ^*data from raw suppliers

morpholine-2-carboxylicacid ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-MORPHOLINECARBOXYLIC ACID HCL

There total 2 articles about 2-MORPHOLINECARBOXYLIC ACID HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(tert-butoxycarbonyl)morpholine-2-carboxylic acid (189321-66-2) → 2-carboxymorpholine acid (300582-83-6,154731-81-4)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; for 1h;

Reference yield:

→ 2-carboxymorpholine acid (300582-83-6,154731-81-4)

Guidance literature:

Reference yield: 46.0%

methanol (67-56-1) + 2-carboxymorpholine acid (300582-83-6,154731-81-4) → methyl 2-morpholine carboxylate hydrochloride (937063-34-8)

Guidance literature:

With thionyl chloride; at 0 - 20 ℃; for 5h; Reflux;

upstream raw materials:

4-(tert-butoxycarbonyl)morpholine-2-carboxylic acid

Downstream raw materials:

C₂₅H₂₇FN₄O₂

4-((6-(2-bromo-4-fluorophenyl)-5-(ethoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholine-2-carboxylic acid

methyl 2-morpholine carboxylate hydrochloride