2,4-Dichloro-5-ethoxyaniline

Base Information

Chemical Name:2,4-Dichloro-5-ethoxyaniline
CAS No.:380844-01-9
Molecular Formula:C8H9 Cl2 N O
Molecular Weight:206.072
Hs Code.:
DSSTox Substance ID:DTXSID80471719
Wikidata:Q82300365
Mol file:380844-01-9.mol

Synonyms:2,4-Dichloro-5-ethoxyaniline;380844-01-9;SCHEMBL25658779;DTXSID80471719;EN300-1154105

Suppliers and Price of 2,4-Dichloro-5-ethoxyaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2,4-Dichloro-5-ethoxyaniline

Chemical Property:

PSA：35.25000
LogP:3.55550
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:205.0061193
Heavy Atom Count:12
Complexity:145

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=C(C=C(C(=C1)N)Cl)Cl

Technology Process of 2,4-Dichloro-5-ethoxyaniline

There total 2 articles about 2,4-Dichloro-5-ethoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 65979-66-0
4,6-dichloro-3-ethoxyacetanilide

: 380844-01-9
2,4-dichloro-5-ethoxyaniline

Guidance literature:: With sodium hydroxide; In ethanol; for 3h; Heating;
DOI:10.1021/jm0102250

Reference yield:

: 67669-19-6
N-(2,4-dichloro-5-hydroxyphenyl)acetamide

: 380844-01-9
2,4-dichloro-5-ethoxyaniline

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / K₂CO₃ / acetone / 4 h / Heating

2: 88 percent / aq. NaOH / ethanol / 3 h / Heating

With sodium hydroxide; potassium carbonate; In ethanol; acetone;
DOI:10.1021/jm0102250

Reference yield: 60.0%

: 214470-55-0
4-chloro-6,7-dimethoxyquinoline-3-carbonitrile

: 380844-01-9
2,4-dichloro-5-ethoxyaniline

: 4-(2,4-dichloro-5-ethoxy-phenylamino)-6,7-dimethoxy-quinoline-3-carbonitrile

Guidance literature:: 2,4-dichloro-5-ethoxyaniline; With sodium hydride; In tetrahydrofuran; for 1h; Heating;

4-chloro-6,7-dimethoxyquinoline-3-carbonitrile; In tetrahydrofuran; Further stages.; Heating;
DOI:10.1021/jm0102250