(R,R)-N-BENZYL-3,4-TRANS-DIMESOLATE PYRROLIDINE

Base Information

Chemical Name:(R,R)-N-BENZYL-3,4-TRANS-DIMESOLATE PYRROLIDINE
CAS No.:380357-38-0
Molecular Formula:C13H19 N O6 S2
Molecular Weight:349.429
Hs Code.:
Mol file:380357-38-0.mol

Synonyms:3,4-Pyrrolidinediol,1-(phenylmethyl)-, dimethanesulfonate (ester), (3R,4R)- (9CI);

Suppliers and Price of (R,R)-N-BENZYL-3,4-TRANS-DIMESOLATE PYRROLIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(R,R)-N-BENZYL-3,4-TRANS-DIMESOLATE PYRROLIDINE 95.00%
5MG
$ 499.61

Total 3 raw suppliers

Chemical Property of (R,R)-N-BENZYL-3,4-TRANS-DIMESOLATE PYRROLIDINE

Chemical Property:

PSA：106.74000
LogP:2.29130

Purity/Quality:

95% ^*data from raw suppliers

(R,R)-N-BENZYL-3,4-TRANS-DIMESOLATE PYRROLIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (R,R)-N-BENZYL-3,4-TRANS-DIMESOLATE PYRROLIDINE

There total 3 articles about (R,R)-N-BENZYL-3,4-TRANS-DIMESOLATE PYRROLIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 124-63-0
methanesulfonyl chloride

: 163439-82-5,330152-66-4
(3R,4R)-1-benzyl-3,4-pyrrolidinediol

: 380357-38-0,1227269-36-4
(3R,4R)-1-Benzyl-3,4-bis(methylsulfonyloxy)pyrrolidin

Guidance literature:: With triethylamine; at 0 ℃;
DOI:10.1039/c5sm01684c

Reference yield:

: 187032-53-7
(3S,4S)-1-N-benzyl-3,4-dihydroxypyrrolidine-2,6-dione

: 380357-38-0,1227269-36-4
(3R,4R)-1-Benzyl-3,4-bis(methylsulfonyloxy)pyrrolidin

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) BF₃*Et₂O, NaBH₄, 2.) NaF, 6 N HCl / 1.) diglycol dimethyl ether, 70 deg C, 2.) diglycol dimethyl ether, 100 deg C

2: triethylamine / CH₂Cl₂ / Ambient temperature

With hydrogenchloride; sodium tetrahydroborate; boron trifluoride diethyl etherate; sodium fluoride; triethylamine; In dichloromethane;

Reference yield:

: 100-46-9
benzylamine

: 380357-38-0,1227269-36-4
(3R,4R)-1-Benzyl-3,4-bis(methylsulfonyloxy)pyrrolidin

Guidance literature:: Multi-step reaction with 3 steps

1: xylene / Heating

2: 1.) BF₃*Et₂O, NaBH₄, 2.) NaF, 6 N HCl / 1.) diglycol dimethyl ether, 70 deg C, 2.) diglycol dimethyl ether, 100 deg C

3: triethylamine / CH₂Cl₂ / Ambient temperature

With hydrogenchloride; sodium tetrahydroborate; boron trifluoride diethyl etherate; sodium fluoride; triethylamine; In dichloromethane; xylene;