tert-butyl (3R)-3-[benzyl-[(1S)-1-phenylethyl]amino]-3-phenyl-propanoate

Base Information

Chemical Name:tert-butyl (3R)-3-[benzyl-[(1S)-1-phenylethyl]amino]-3-phenyl-propanoate
CAS No.:265669-72-5
Molecular Formula:C₂₈H₃₃NO₂
Molecular Weight:415.576
Hs Code.:

Synonyms:tert-butyl (3R,αS)-3-[N-benzyl-N-(α-methylbenzyl)amino]-3-phenylpropanoate

Suppliers and Price of tert-butyl (3R)-3-[benzyl-[(1S)-1-phenylethyl]amino]-3-phenyl-propanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl (3R)-3-[benzyl-[(1S)-1-phenylethyl]amino]-3-phenyl-propanoate

Chemical Property:

Vapor Pressure:0mmHg at 25°C

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

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Technology Process of tert-butyl (3R)-3-[benzyl-[(1S)-1-phenylethyl]amino]-3-phenyl-propanoate

There total 6 articles about tert-butyl (3R)-3-[benzyl-[(1S)-1-phenylethyl]amino]-3-phenyl-propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 17480-69-2
(S)-N-benzyl-1-phenylethylamine

: 14990-09-1
tert-butyl cinnamate

: 265669-72-5
tert-butyl (3R,αS)-3-[N-benzyl-N-(α-methylbenzyl)amino]-3-phenylpropanoate

Guidance literature:: (S)-N-benzyl-1-phenylethylamine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

tert-butyl cinnamate; In tetrahydrofuran; hexane; at -78 ℃; for 1.5h; Inert atmosphere;

With ammonium chloride; In tetrahydrofuran; hexane; water; at -78 - 0 ℃; optical yield given as %de; diastereoselective reaction;
DOI:10.1021/jo101600c

Reference yield: 89.0%

: 14990-09-1
tert-butyl cinnamate

: 17480-69-2
(S)-N-benzyl-1-phenylethylamine

: 265669-72-5
tert-butyl (3R,αS)-3-[N-benzyl-N-(α-methylbenzyl)amino]-3-phenylpropanoate

Guidance literature:: (S)-N-benzyl-1-phenylethylamine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

tert-butyl cinnamate; In tetrahydrofuran; hexane; at -78 ℃; for 2h; Inert atmosphere;

With water; ammonium chloride; In tetrahydrofuran; hexane; at -78 - 20 ℃; optical yield given as %de; diastereoselective reaction; Inert atmosphere;
DOI:10.1016/j.tetasy.2011.06.008