(4S)-4-benzyl-3-(3-phenylprop-2-enoyl)-1,3-oxazolidin-2-one

Base Information Edit

Chemical Name:(4S)-4-benzyl-3-(3-phenylprop-2-enoyl)-1,3-oxazolidin-2-one
CAS No.:133812-18-7
Molecular Formula:C19H17NO3
Molecular Weight:307.349
Hs Code.:
DSSTox Substance ID:DTXSID601154763
Mol file:133812-18-7.mol

Synonyms:133812-18-7;DTXSID601154763;(4S)-3-(1-Oxo-3-phenyl-2-propen-1-yl)-4-(phenylmethyl)-2-oxazolidinone

Suppliers and Price of (4S)-4-benzyl-3-(3-phenylprop-2-enoyl)-1,3-oxazolidin-2-one

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4S)-4-benzyl-3-(3-phenylprop-2-enoyl)-1,3-oxazolidin-2-one Edit

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:307.12084340
Heavy Atom Count:23
Complexity:448

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(N(C(=O)O1)C(=O)C=CC2=CC=CC=C2)CC3=CC=CC=C3
Isomeric SMILES:C1[C@@H](N(C(=O)O1)C(=O)C=CC2=CC=CC=C2)CC3=CC=CC=C3

Technology Process of (4S)-4-benzyl-3-(3-phenylprop-2-enoyl)-1,3-oxazolidin-2-one

There total 3 articles about (4S)-4-benzyl-3-(3-phenylprop-2-enoyl)-1,3-oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 90719-32-7
(S)-4-Benzyl-2-oxazolidinone

: 621-82-9
Cinnamic acid

: 133812-18-7
(S)-4-benzyl-3-(6-(benzyloxy)hex-2-enoyl)oxazolidin-2-one

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 6h;
DOI:10.1055/s-2003-42117

Reference yield: 82.0%

: 90719-32-7
(S)-4-Benzyl-2-oxazolidinone

: 102-92-1,17082-09-6
cinnamoyl chloride

: 133812-18-7
(S)-4-benzyl-3-(6-(benzyloxy)hex-2-enoyl)oxazolidin-2-one

Guidance literature:: (S)-4-Benzyl-2-oxazolidinone; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.333333h; Inert atmosphere;

cinnamoyl chloride; In tetrahydrofuran; at -78 - 0 ℃; for 1.5h;

Reference yield:

: 100-52-7
benzaldehyde

: 137789-54-9
diethyl {2-[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]-2-oxoethyl}phosphonate

: 133812-18-7
(S)-4-benzyl-3-(6-(benzyloxy)hex-2-enoyl)oxazolidin-2-one

Guidance literature:: With N-ethyl-N,N-diisopropylamine; lithium chloride; In acetonitrile; for 4h; Cooling with ice;
DOI:10.1016/j.tet.2011.11.038