3-(2-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE

Base Information

Chemical Name:3-(2-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE
CAS No.:376641-58-6
Molecular Formula:C10H9 F3 O
Molecular Weight:202.17
Hs Code.:
Mol file:376641-58-6.mol

Synonyms:3-(2-Trifluoromethylphenyl)propanal

Suppliers and Price of 3-(2-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Trifluoromethyl)-Benzenepropanal
5mg
$ 345.00

Rieke Metals
3-(2-Trifluoromethyl-phenyl)-propionaldehyde
5g
$ 1728.00

American Custom Chemicals Corporation
3-(2-TRIFLUOROMETHYL-PHENYL)PROPIONALDEHYDE 95.00%
5MG
$ 504.44

Alichem
3-(2'-(Trifluoromethyl)phenyl)propionaldehyde
1g
$ 1519.80

Alichem
3-(2'-(Trifluoromethyl)phenyl)propionaldehyde
500mg
$ 790.55

Alichem
3-(2'-(Trifluoromethyl)phenyl)propionaldehyde
250mg
$ 489.60

Total 19 raw suppliers

Chemical Property of 3-(2-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE

Chemical Property:

Vapor Pressure:0.245mmHg at 25°C
Refractive Index:1.45
Boiling Point:205.856°C at 760 mmHg
Flash Point:92.577°C
PSA：17.07000
Density:1.192g/cm³
LogP:2.83690

Purity/Quality:

97% ^*data from raw suppliers

2-(Trifluoromethyl)-Benzenepropanal ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-(Trifluoromethyl)-Benzenepropanal is an impurity of Cinacalcet (C441800), used in clinical trial in secondary hyperparathyroidism.

Technology Process of 3-(2-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE

There total 8 articles about 3-(2-TRIFLUOROMETHYL-PHENYL)-PROPIONALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.6%

: 191155-81-4
3-(2-(trifluoromethyl)phenyl)propan-1-ol

: 376641-58-6
3-(2-(trifluoromethyl)phenyl)propanal

Guidance literature:

Reference yield: 45.0%

: 444-29-1
2-iodo(trifluoromethyl)benzene

: 107-18-6
allyl alcohol

: 376641-58-6
3-(2-(trifluoromethyl)phenyl)propanal

Guidance literature:: With palladium diacetate; benzyltrimethylammonium chloride; sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 50 ℃; for 4h; Inert atmosphere;
DOI:10.1021/jacs.0c01330

Reference yield:

: 201230-82-2
carbon monoxide

: 395-45-9
o-(trifluoromethyl)styrene

: 376641-58-6
3-(2-(trifluoromethyl)phenyl)propanal

: 21235-72-3
2-(2-trifluoromethylphenyl)propanal

Guidance literature:: With dicarbonyl(acetylacotonato)rhodium(I); C₇₅H₅₄N₄O₈P₂; hydrogen; In dichloromethane; at 20 ℃; for 24h; under 15001.5 Torr; Time; regioselective reaction; Autoclave;
DOI:10.1002/anie.201209582