N,N-Dimethylethylamine

Base Information

• Chemical Name: N,N-Dimethylethylamine
• CAS No.: 598-56-1
• Molecular Formula: C4H11 N
• Molecular Weight: 73.138
• Hs Code.: 29211980
• European Community (EC) Number: 209-940-8
• UNII: 9N5384XVEM
• DSSTox Substance ID: DTXSID4027232
• Nikkaji Number: J60.917J
• Wikipedia: N,N-Dimethylethylamine
• Wikidata: Q16954761
• Pharos Ligand ID: YM7AZZF453A1
• Metabolomics Workbench ID: 143648
• ChEMBL ID: CHEMBL609099
• Mol file: 598-56-1.mol

Synonyms:Ethylamine,N,N-dimethyl- (6CI,7CI,8CI); DMEA; Dimethylethylamine; Methanamine,N-ethyl-N-methyl-; N,N-Dimethylaminoethane; N,N-Dimethylethanamine;N,N-Dimethylethylamine; N-Ethyldimethylamine

Chemical Property of N,N-Dimethylethylamine

Chemical Property:

• Appearance/Colour: colorless liquid
• Vapor Pressure: 8.09 psi ( 20 °C)
• Melting Point: -140 ºC
• Refractive Index: n20/D 1.372(lit.)
• Boiling Point: 36.3 °C at 760 mmHg
• PKA: 9.83±0.28(Predicted)
• Flash Point: -36 ºC
• PSA: 3.24000
• Density: 0.675
• LogP: 0.56790
• Storage Temp.: Flammables area
• Sensitive.: Light Sensitive
• Water Solubility.: SOLUBLE
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 73.089149355
• Heavy Atom Count: 5
• Complexity: 17.6

Purity/Quality:

99.9% ^*data from raw suppliers

Dimethylethylamine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F+,C,F
• Statements: 12-20/22-34-11
• Safety Statements: 3-16-26-36-45-2733/2734/2735-Tranport-port-Tran

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Amines, Aliphatic
• Canonical SMILES: CCN(C)C
• Uses: N,N-Dimethylethylamine is used as adhesive, sealant chemical and process regulator. It acts as an intermediate for quaternary ammonium compounds and is also used as a stabilizer for chlorinated hydrocarbons and vinyl derivatives. It is used in foundries as a catalyst for sand core production. Further, it is employed in the polymerization of polyamides. In addition to this, it is used in the preparation of polypeptide nanogels with self-reinforced endocytoses. N,N-Dimethylethylamine was used in the preparation of pH and reduction dual-responsive polypeptide nanogels with self-reinforced endocytoses.

Technology Process of N,N-Dimethylethylamine

There total 54 articles about N,N-Dimethylethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N,N-dimethylacetamide dimethyl acetal (18871-66-4) → N,N-dimethyl-ethanamine (598-56-1)

Guidance literature:

With [1,4-bis(diphenylphosphino)butane](1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; hydrogen; at 25 ℃; for 0.5h; under 3750.38 Torr; Reagent/catalyst;

DOI:10.1002/cctc.201701287

Reference yield: 95.4%

3-(2'-methoxyphenyl)propenoic acid (6099-03-2) + dimethyl amine (124-40-3) → N,N-dimethyl-ethanamine (598-56-1) + phenol (108-95-2,27073-41-2)

Guidance literature:

In water; N,N-dimethyl-formamide; at 199.84 ℃; for 4h; under 7500.75 Torr; Inert atmosphere;

DOI:10.1039/d1sc05231d

Reference yield: 93.5%

4-Vinylphenol (2628-17-3,24979-70-2) + dimethyl amine (124-40-3) → N,N-dimethyl-ethanamine (598-56-1) + phenol (108-95-2,27073-41-2)

Guidance literature:

In water; N,N-dimethyl-formamide; at 199.84 ℃; for 1h; under 7500.75 Torr; Inert atmosphere;

DOI:10.1039/d1sc05231d

upstream raw materials:

methyl magnesium iodide

N,N-Dimethylamino acetonitrile

formic acid

N-ethylhexamethylenetetrammonium bromide

Downstream raw materials:

ethyl-[2-(4-chloro-phenoxy)-ethyl]-dimethyl-ammonium; bromide

N-tosyl-N',N'-dimethylformamidine

C₃₁H₅₆NS₃⁽¹⁺⁾*Cl^(1-)

ethyltrimethylammonium iodide

Refernces

• 1、 Delepine,Demars. "-". . . Retrieved 1924.
• 2、 Bisai, Milan Kumar,Gour, Kritika,Das, Tamal,Vanka, Kumar,Sen, Sakya S.. "Lithium compound catalyzed deoxygenative hydroboration of primary, secondary and tertiary amides". supporting information. p. 2354 - 2358. Retrieved 2021/03/03.
• 3、 Cheng, Xiaomeng,Dong, Minghua,Han, Buxing,Liu, Huizhen,Liu, Shulin,Shen, Xiaojun,Wang, Zhenpeng,Xin, Yu,Yang, Junjuan. "Organic amine mediated cleavage of Caromatic-Cαbonds in lignin and its platform molecules". . p. 15110 - 15115. Retrieved 2021/12/04.