ditetradecyl N-<4-<<6-(trimethylammonio)hexyl>oxy>benzoyl>-L-glutamate bromide

Base Information

• Chemical Name: ditetradecyl N-<4-<<6-(trimethylammonio)hexyl>oxy>benzoyl>-L-glutamate bromide
• CAS No.: 107086-88-4
• Molecular Formula: Br*C₄₉H₈₉N₂O₆
• Molecular Weight: 882.159
• Mol file: 107086-88-4.mol

Synonyms:ditetradecyl N-<4-<<6-(trimethylammonio)hexyl>oxy>benzoyl>-L-glutamate bromide

Chemical Property of ditetradecyl N-<4-<<6-(trimethylammonio)hexyl>oxy>benzoyl>-L-glutamate bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ditetradecyl N-<4-<<6-(trimethylammonio)hexyl>oxy>benzoyl>-L-glutamate bromide

There total 5 articles about ditetradecyl N-<4-<<6-(trimethylammonio)hexyl>oxy>benzoyl>-L-glutamate bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

ditetradecyl N-<4-<(6-bromohexyl)oxy>benzoyl>-L-glutamate (130860-39-8) + trimethylamine (75-50-3) → ditetradecyl N-<4-<<6-(trimethylammonio)hexyl>oxy>benzoyl>-L-glutamate bromide (107086-88-4)

Guidance literature:

In benzene; for 120h; Ambient temperature;

DOI:10.1021/ja00002a034

Reference yield:

Ethyl 4-hydroxybenzoate (120-47-8) → ditetradecyl N-<4-<<6-(trimethylammonio)hexyl>oxy>benzoyl>-L-glutamate bromide (107086-88-4)

Guidance literature:

Multi-step reaction with 4 steps

1: KOH / ethanol / 7 h / Heating

2: 30percent aq. hydrobromic acid / acetic acid; ethanol / 7 h / Heating

3: 86 percent / triethylamine, diethyl phosphocyanide / tetrahydrofuran / 24 h / Ambient temperature

4: 82 percent / benzene / 120 h / Ambient temperature

With potassium hydroxide; diethyl cyanophosphonate; hydrogen bromide; triethylamine; In tetrahydrofuran; ethanol; acetic acid; benzene;

DOI:10.1021/ja00002a034

Reference yield:

1 ,6-dibromohexane (629-03-8) → ditetradecyl N-<4-<<6-(trimethylammonio)hexyl>oxy>benzoyl>-L-glutamate bromide (107086-88-4)

Guidance literature:

Multi-step reaction with 4 steps

1: KOH / ethanol / 7 h / Heating

2: 30percent aq. hydrobromic acid / acetic acid; ethanol / 7 h / Heating

3: 86 percent / triethylamine, diethyl phosphocyanide / tetrahydrofuran / 24 h / Ambient temperature

4: 82 percent / benzene / 120 h / Ambient temperature

With potassium hydroxide; diethyl cyanophosphonate; hydrogen bromide; triethylamine; In tetrahydrofuran; ethanol; acetic acid; benzene;

DOI:10.1021/ja00002a034

upstream raw materials:

ditetradecyl N-<4-<(6-bromohexyl)oxy>benzoyl>-L-glutamate

trimethylamine

Ethyl 4-hydroxybenzoate

1 ,6-dibromohexane