2-METHOXYBIPHENYL

Base Information

• Chemical Name: 2-METHOXYBIPHENYL
• CAS No.: 292625-97-9
• Molecular Formula: C₁₃H₁₂O
• Molecular Weight: 184.238
• Mol file: 292625-97-9.mol

Synonyms:O-PHENYLANISOLE;O-METHOXYBIPHENYL;O-METHOXYDIPHENYL;2-PHENYL-ANISOL;2-PHENYLANISOLE;2-METHOXYBIPHENYL;METHYL DIPHENYL ETHER

Chemical Property of 2-METHOXYBIPHENYL

Chemical Property:

• Melting Point: 30-33 °C(lit.)
• Refractive Index: n20/D 1.61(lit.)
• Boiling Point: 274 °C(lit.)
• Flash Point: 101.3°C
• PSA: 9.23000
• Density: 1.03g/cm³
• LogP: 3.36220

Purity/Quality:

99% ^*data from raw suppliers

2-Methoxybiphenyl 98% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 33
• Safety Statements: 24/25-23

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-METHOXYBIPHENYL

There total 313 articles about 2-METHOXYBIPHENYL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

methanol (67-56-1) + bis(2,2'-bisphenylylene)selenurane (19615-37-3) → dibenzo[b,d]selenophene (244-95-1) + 2-methoxy-1,1'-biphenyl (86-26-0,292625-97-9)

Guidance literature:

In tetrahydrofuran; at -78 - 20 ℃;

DOI:10.1246/cl.1994.889

Reference yield: 60.0%

perbenzoyl p-nitrophenyl carbonate (42464-09-5) + methoxybenzene (100-66-3) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + 4-methoxylbiphenyl (613-37-6) + 2-methoxy-1,1'-biphenyl (86-26-0,292625-97-9) + 3-methoxybiphenyl (2113-56-6)

Guidance literature:

at 180 ℃; for 5h; Further byproducts given;

DOI:10.1021/ja00405a043

Reference yield: 30.0%

N-<(o-phenylthio)phenyl>formamide (1489-24-3) + methoxybenzene (100-66-3) → 2(3H)-Benzothiazolone (934-34-9) + 4-methoxylbiphenyl (613-37-6) + 2-methoxy-1,1'-biphenyl (86-26-0,292625-97-9) + 3-methoxybiphenyl (2113-56-6)

Guidance literature:

With di-tert-butyl peroxide; at 110 ℃; for 48h; Yield given;

DOI:10.1039/P19810003164

upstream raw materials:

diazomethane

2-Phenylphenol

6-methoxy-biphenyl-3,4'-dicarboxylic acid

3-amino-2'-methoxybiphenyl

Downstream raw materials:

(5-benzyl-biphenyl-2-yl)-methyl ether

4-methoxy-3-phenyl-benzophenone

1-(6-methoxy-biphenyl-3-yl)-ethanone

6H-benzo[c]chromen-6-one

Refernces

• 1、 Tuerkmen, Hayati,Kani, Ibrahim. "Synthesis, characterization, and reactivity of palladium(II) complexes containing piperidoimidazolin-2-ylidene". . p. 489 - 493. Retrieved 2013.
• 2、 Kim, Young-O,You, Jae Myoung,Jang, Hyung-Seok,Choi, Seo Keong,Jung, Byeong Yun,Kang, Onyu,Kim, Jung Won,Lee, Yoon-Sik. "Eumelanin as a support for efficient palladium nanoparticle catalyst for Suzuki coupling reaction of aryl chlorides in water". . p. 2149 - 2152. Retrieved 2017.
• 3、 Dankwardt, John W.. "Transition metal catalyzed cross-coupling of aryl Grignard reagents with aryl fluorides via Pd- or Ni-activation of the C-F bond: An efficient synthesis of unsymmetrical biaryls - Application of microwave technology in ligand and catalyst screening". . p. 932 - 938. Retrieved 2005.
• 4、 Huang, Yuanbiao,Zheng, Zhaoliang,Liu, Tianfu,Lü, Jian,Lin, Zujin,Li, Hongfang,Cao, Rong. "Palladium nanoparticles supported on amino functionalized metal-organic frameworks as highly active catalysts for the Suzuki-Miyaura cross-coupling reaction". . p. 27 - 31. Retrieved 2011.
• 5、 Bananezhad, Behjat,Islami, Mohammad Reza,Ghonchepour, Ehsan,Mostafavi, Hamid,Tikdari, Ahmad Momeni,Rafiei, Hamid Reza. "Bentonite clay as an efficient substrate for the synthesis of the super stable and recoverable magnetic nanocomposite of palladium (Fe3O4/Bentonite-Pd)". . p. 192 - 200. Retrieved 2019.
• 6、 Borkowski, Tomasz,Dobosz, Justyna,Tylus, W?odzimierz,Trzeciak, Anna M.. "Palladium supported on Al2O3-CeO2 modified with ionic liquids as a highly active catalyst of the Suzuki-Miyaura cross-coupling". . p. 87 - 94. Retrieved 2014.
• 7、 Arvela, Riina K.,Leadbeater, Nicholas E.. "Suzuki coupling of aryl chlorides with phenylboronic acid in water, using microwave heating with simultaneous cooling". . p. 2101 - 2104. Retrieved 2005.
• 8、 Sarmah, Chandan,Sahu, Debojeet,Das, Pankaj. "An effective strategy for immobilizing a homogeneous palladium complex onto silica: Efficient and reusable catalyst for Suzuki-Miyaura reactions". . p. 75 - 78. Retrieved 2013.
• 9、 Gao, Shuiying,Zheng, Zhaoliang,Lue, Jian,Cao, Rong. "Progressive release of a palladium-pyridyl complex from a layer-by-layer multilayer and illustrative application to catalytic Suzuki coupling". . p. 7584 - 7586. Retrieved 2010.
• 10、 Bedford, Robin B.,Cazin, Catherine S. J.,Hazelwood, Samantha L.. "Simple tricyclohexylphosphine-palladium complexes as efficient catalysts for the Stille coupling of deactivated aryl chlorides". . p. 2608 - 2609. Retrieved 2002.