C₁₉H₁₉NO₆

Base Information

• Chemical Name: C₁₉H₁₉NO₆
• CAS No.: 1012794-99-8
• Molecular Formula: C₁₉H₁₉NO₆
• Molecular Weight: 357.363
• Mol file: 1012794-99-8.mol

Synonyms:C₁₉H₁₉NO₆

Chemical Property of C₁₉H₁₉NO₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of C₁₉H₁₉NO₆

There total 8 articles about C₁₉H₁₉NO₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-[3,5-dimethyl-4-(4-nitro-benzyloxy)-phenyl]-4-oxo-butyric acid methyl ester (948995-57-1) → C19H19NO6 (1012794-99-8)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 3h;

DOI:10.1080/00397911.2011.619678

Reference yield:

4-(4-hydroxy-3,5-dimethylphenyl)-4-oxobutyric acid methyl ester (52246-10-3) → C19H19NO6 (1012794-99-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / K₂CO₃ / dimethylformamide / 3 h / 20 °C

2: aq. NaOH / tetrahydrofuran / 3 h / 20 °C

With sodium hydroxide; potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1021/jo070621b

Reference yield:

4-(4-methoxy-3,5-dimethylphenyl)-4-oxobutyric acid methyl ester (948995-56-0) → C19H19NO6 (1012794-99-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 65 percent / BBr₃ / CH₂Cl₂ / 12 h / -5 °C

2: 95 percent / K₂CO₃ / dimethylformamide / 3 h / 20 °C

3: aq. NaOH / tetrahydrofuran / 3 h / 20 °C

With sodium hydroxide; boron tribromide; potassium carbonate; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jo070621b

upstream raw materials:

4-[3,5-dimethyl-4-(4-nitro-benzyloxy)-phenyl]-4-oxo-butyric acid methyl ester

4-(4-methoxy-3,5-dimethylphenyl)-4-oxobutyric acid methyl ester

2-methoxy-1,3-dimethylbenzene

4-(4-methoxy-3,5-dimethylphenyl)-4-oxobutanoic acid

Downstream raw materials:

4-[3,5-dimethyl-4-(4-nitro-benzyloxy)-phenyl]-4-oxo-butyric acid 2,5-dioxo-pyrrolidin-1-yl ester

N-[2-(2-azidoethoxy)ethyl]-4-[3,5-dimethyl-4-(4-nitrobenzyloxy)phenyl]-4-oxobutyramide

C₄₀H₄₉N₅O₁₆

C₅₂H₆₅N₅O₂₄

Refernces

• 1、 Maki, Toshihide,Ishida, Koji. "Photocleavable molecule for laser desorption ionization mass spectrometry". . p. 6427 - 6433. Retrieved 2008/02/10.