5-Iodo-3-methylpyridin-2-ol

Base Information

Chemical Name:5-Iodo-3-methylpyridin-2-ol
CAS No.:289681-47-6
Molecular Formula:C6H6 I N O
Molecular Weight:235.024
Hs Code.:2933399090
DSSTox Substance ID:DTXSID00369427
Nikkaji Number:J2.203.834F
Wikidata:Q82156498
Mol file:289681-47-6.mol

Synonyms:5-iodo-3-methylpyridin-2-ol;289681-47-6;2-Hydroxy-5-iodo-3-methylpyridine;5-iodo-3-methyl-1H-pyridin-2-one;5-iodo-3-methyl-1,2-dihydropyridin-2-one;MFCD04111315;SCHEMBL8138214;DTXSID00369427;SMXYHYVNDWELHQ-UHFFFAOYSA-N;HMS1666D22;AMY28754;5-Iodo-3-methyl-2(1H)-pyridinone;5-Iodo-3-methylpyridin-2(1H)-one;CCG-40873;3-Methyl-5-iodopyridine-2(1H)-one;AKOS015853760;BS-2052;DS-3867;AC-24300;SY041380;A5452;BB 0261871;CS-0041742;FT-0682280;EN300-85874;I11362;SR-01000630984-1;Z1258842308

Suppliers and Price of 5-Iodo-3-methylpyridin-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
5-Iodo-3-methylpyridin-2-ol 95%
500mg
$ 405.00

Crysdot
5-Iodo-3-methylpyridin-2-ol 95+%
5g
$ 119.00

Chemenu
5-Iodo-3-methylpyridin-2-ol 95%
25g
$ 359.00

Chemenu
5-Iodo-3-methylpyridin-2-ol 95%
5g
$ 122.00

Chemenu
5-Iodo-3-methylpyridin-2-ol 95%
10g
$ 204.00

Chemcia Scientific
5-Iodo-3-methyl-pyridin-2-ol ＞95%
10 G
$ 185.00

Chemcia Scientific
5-Iodo-3-methyl-pyridin-2-ol ＞95%
5 G
$ 110.00

American Custom Chemicals Corporation
5-IODO-3-METHYLPYRIDIN-2-OL 95.00%
500MG
$ 864.17

American Custom Chemicals Corporation
5-IODO-3-METHYLPYRIDIN-2-OL 95.00%
1G
$ 962.35

Ambeed
5-Iodo-3-methylpyridin-2-ol 97%
5g
$ 38.00

Total 18 raw suppliers

Chemical Property of 5-Iodo-3-methylpyridin-2-ol

Chemical Property:

Boiling Point:312.3°Cat760mmHg
Flash Point:142.7°C
PSA：33.12000
Density:1.94g/cm³
LogP:1.70020
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:234.94941
Heavy Atom Count:9
Complexity:205

Purity/Quality:

99%, ^*data from raw suppliers

5-Iodo-3-methylpyridin-2-ol 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CNC1=O)I

Technology Process of 5-Iodo-3-methylpyridin-2-ol

There total 2 articles about 5-Iodo-3-methylpyridin-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 166266-19-9
2-amino-3-methyl-5-iodopyridine

: 289681-47-6
5-iodo-3-methyl-1H-pyridin-2-one

Guidance literature:: 2-amino-3-methyl-5-iodopyridine; With sulfuric acid; sodium nitrite; at 60 ℃; for 0.25h;

With boric acid; In water; at 0 - 100 ℃;
DOI:10.1006/bioo.2001.1209

Reference yield:

: 1603-40-3
3-methylpyridin-2-ylamine

: 289681-47-6
5-iodo-3-methyl-1H-pyridin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: 73 percent / periodic acid dihydrate; iodine; sulfuric acid / acetic acid; H₂O / 4 h / 80 °C

2.1: conc. sulfuric acid; sodium nitrite / 0.25 h / 60 °C

2.2: 75 percent / boric acid / 100 °C

With sulfuric acid; iodine; periodic acid; sodium nitrite; In water; acetic acid; 1.1: Iodination / 2.1: Diazotization / 2.2: Oxidation;
DOI:10.1021/ja000686v