N-nosyl-L-isoleucine chloride

Base Information

• Chemical Name: N-nosyl-L-isoleucine chloride
• CAS No.: 852853-20-4
• Molecular Formula: C₁₂H₁₅ClN₂O₅S
• Molecular Weight: 334.78
• Mol file: 852853-20-4.mol

Synonyms:N-nosyl-L-isoleucine chloride

Chemical Property of N-nosyl-L-isoleucine chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-nosyl-L-isoleucine chloride

There total 3 articles about N-nosyl-L-isoleucine chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-methyl-2-(4-nitrophenylsulphonamido)pentanoic acid (852852-81-4) → N-nosyl-L-isoleucine chloride (852853-20-4)

Guidance literature:

With thionyl chloride; In dichloromethane; Heating;

DOI:10.1021/jo070438i

Reference yield:

L-isoleucine (73-32-5,959215-79-3,18875-42-8) → N-nosyl-L-isoleucine chloride (852853-20-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / thionyl chloride / CH₂Cl₂ / Heating

With thionyl chloride; In dichloromethane;

DOI:10.1021/jo070438i

Reference yield:

4-Nitrobenzenesulfonyl chloride (98-74-8) → N-nosyl-L-isoleucine chloride (852853-20-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / thionyl chloride / CH₂Cl₂ / Heating

With thionyl chloride; In dichloromethane;

DOI:10.1021/jo070438i

upstream raw materials:

3-methyl-2-(4-nitrophenylsulphonamido)pentanoic acid

L-isoleucine

4-Nitrobenzenesulfonyl chloride

Downstream raw materials:

N-(N-(N-nosyl-L-isoleucyl)-D-alanyl)-L-valine methyl ester

N-methyl-N-nosyl-L-isoleucyldiazomethane

N-(N-(N-methyl-N-nosyl-L-isoleucyl)-D-alanyl)-L-valine methyl ester

N-(N-(N-nosyl-L-valyl)-N-methyl-L-isoleucyl)-L-alanine methyl ester