C₂₅H₄₁NO₆Si

Base Information

• Chemical Name: C₂₅H₄₁NO₆Si
• CAS No.: 1466431-00-4
• Molecular Formula: C₂₅H₄₁NO₆Si
• Molecular Weight: 479.689
• Mol file: 1466431-00-4.mol

Synonyms:C₂₅H₄₁NO₆Si

Chemical Property of C₂₅H₄₁NO₆Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₄₁NO₆Si

There total 6 articles about C₂₅H₄₁NO₆Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

C25H43NO7Si (1466430-99-8) → C25H41NO6Si (1466431-00-4)

Guidance literature:

With diethylamino-sulfur trifluoride; In dichloromethane; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1055/s-0033-1338493

Reference yield:

(S)-tert-butyl(1-(4-methoxybenzyloxy)-2,2-dimethylhex-5-en-3-yloxy)dimethylsilane (1414941-22-2) → C25H41NO6Si (1466431-00-4)

Guidance literature:

Multi-step reaction with 4 steps

1: ozone; triphenylphosphine / dichloromethane / -78 - 20 °C

2: sodium chlorite; 2-methyl-but-2-ene; sodium dihydrogenphosphate / tert-butyl alcohol; water / 1.5 h / 20 °C / Inert atmosphere

3: 4-methyl-morpholine; isobutyl chloroformate / tetrahydrofuran / -30 - 20 °C / Inert atmosphere

4: diethylamino-sulfur trifluoride / dichloromethane / -78 - 20 °C / Inert atmosphere

With 4-methyl-morpholine; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; diethylamino-sulfur trifluoride; ozone; triphenylphosphine; isobutyl chloroformate; In tetrahydrofuran; dichloromethane; water; tert-butyl alcohol;

DOI:10.1055/s-0033-1338493

Reference yield:

(S)-1-(4-methoxybenzyloxy)-2,2-dimethylhex-5-en-3-ol (885674-86-2) → C25H41NO6Si (1466431-00-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 2,6-dimethylpyridine / dichloromethane / 0 - 20 °C / Inert atmosphere

2: ozone; triphenylphosphine / dichloromethane / -78 - 20 °C

3: sodium chlorite; 2-methyl-but-2-ene; sodium dihydrogenphosphate / tert-butyl alcohol; water / 1.5 h / 20 °C / Inert atmosphere

4: 4-methyl-morpholine; isobutyl chloroformate / tetrahydrofuran / -30 - 20 °C / Inert atmosphere

5: diethylamino-sulfur trifluoride / dichloromethane / -78 - 20 °C / Inert atmosphere

With 4-methyl-morpholine; 2,6-dimethylpyridine; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; diethylamino-sulfur trifluoride; ozone; triphenylphosphine; isobutyl chloroformate; In tetrahydrofuran; dichloromethane; water; tert-butyl alcohol;

DOI:10.1055/s-0033-1338493

upstream raw materials:

(S)-tert-butyl(1-(4-methoxybenzyloxy)-2,2-dimethylhex-5-en-3-yloxy)dimethylsilane

(S)-3-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)-4,4-dimethylpentanoic acid

t-butyldimethylsiyl triflate

(S)-1-(4-methoxybenzyloxy)-2,2-dimethylhex-5-en-3-ol

Downstream raw materials:

(S)-methyl 2-[2-(tert-butyldimethylsilyloxy)-4-(4-methoxybenzyloxy)-3,3-dimethylbutyl]oxazole-4-carboxylate

(2S,5S,7S)-7-[(tert-butyldimethylsilyl)oxy]-5-hydroxy-1-[(4-methoxybenzyl)oxy]-8-{4-[(S)-1-methoxybut-3-en-1-yl]oxazol-2-yl}-2,6,6-trimethyloctan-3-one

(2S,5R,7S)-7-[(tert-butyldimethylsilyl)oxy]-5-hydroxy-1-[(4-methoxybenzyl)oxy]-8-{4-[(S)-1-methoxybut-3-en-1-yl]oxazol-2-yl}-2,6,6-trimethyloctan-3-one

(2S,6S,7S)-2-[(tert-Butyldimethylsilyl)oxy]-6-methoxy-8-[(4-methoxybenzyl)oxy]-1-{4-[(S)-1-methoxybut-3-en-1-yl]oxazol-2-yl}-3,3,7-trimethyloctan-4-one