1-[(1R,2S,5R)-(-)-menthoxymethyl]-3-methylimidazolium chloride

Base Information

• Chemical Name: 1-[(1R,2S,5R)-(-)-menthoxymethyl]-3-methylimidazolium chloride
• CAS No.: 945617-59-4
• Molecular Formula: C₁₅H₂₇N₂O*Cl
• Molecular Weight: 286.845
• Mol file: 945617-59-4.mol

Synonyms:1-[(1R,2S,5R)-(-)-menthoxymethyl]-3-methylimidazolium chloride

Chemical Property of 1-[(1R,2S,5R)-(-)-menthoxymethyl]-3-methylimidazolium chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-[(1R,2S,5R)-(-)-menthoxymethyl]-3-methylimidazolium chloride

There total 2 articles about 1-[(1R,2S,5R)-(-)-menthoxymethyl]-3-methylimidazolium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-methyl-1H-imidazole (616-47-7) + (1R,2S,5R)-1-(chloromethoxy)-2-isopropyl-5-methylcyclohexane (26127-08-2,144177-48-0) → 1-[(1R,2S,5R)-(-)-menthoxymethyl]-3-methylimidazolium chloride (945617-59-4)

Guidance literature:

at 20 ℃;

DOI:10.1039/b503239c

Reference yield:

(-)-menthol (2216-51-5) → 1-[(1R,2S,5R)-(-)-menthoxymethyl]-3-methylimidazolium chloride (945617-59-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride

2: hexane / 20 °C

With hydrogenchloride; In hexane;

DOI:10.1016/j.molliq.2017.07.012

Reference yield: 84.0%

1-[(1R,2S,5R)-(-)-menthoxymethyl]-3-methylimidazolium chloride (945617-59-4) + silver(l) oxide (20667-12-3) → [(1-methyl-3-((+)-methylmenthoxide-imidazolin-2-ylidene)2Ag-AgCl2]

Guidance literature:

In dichloromethane; Ag2O added to soln. of 1-methyl-3-(+)-methylmentoxide imidazolium chloride in CH2Cl2, mixt. stirred at room temp. for 4 h; soln. filtered through Celite, filtrate evapd. under vac.;

DOI:10.1039/b503239c

upstream raw materials:

1-methyl-1H-imidazole

(1R,2S,5R)-1-(chloromethoxy)-2-isopropyl-5-methylcyclohexane

(-)-menthol