N,N-diethyl-1-phenylmethanesulfonamide

Base Information

Chemical Name:N,N-diethyl-1-phenylmethanesulfonamide
CAS No.:62162-78-1
Molecular Formula:C11H17 N O2 S
Molecular Weight:227.327
Hs Code.:
NSC Number:130926
DSSTox Substance ID:DTXSID30977756
Nikkaji Number:J2.994.020G
Wikidata:Q82963049

Synonyms:N,N-diethyl-1-phenylmethanesulfonamide;62162-78-1;NSC130926;SCHEMBL3192672;DTXSID30977756;HMS1694M06;STK000711;AKOS003260376;NSC-130926

Suppliers and Price of N,N-diethyl-1-phenylmethanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of N,N-diethyl-1-phenylmethanesulfonamide

Chemical Property:

Vapor Pressure:7.5E-05mmHg at 25°C
Boiling Point:342.5°Cat760mmHg
Flash Point:160.9°C
Density:1.136g/cm³
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:227.09799996
Heavy Atom Count:15
Complexity:259

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)S(=O)(=O)CC1=CC=CC=C1

Technology Process of N,N-diethyl-1-phenylmethanesulfonamide

There total 5 articles about N,N-diethyl-1-phenylmethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 150-60-7
dibenzyl disulphide

: 109-89-7
diethylamine

: 62162-78-1
N,N-diethyl-1-phenylmethanesulfonamide

Guidance literature:: dibenzyl disulphide; With tert-butylhypochlorite; water; In acetonitrile; at 0 ℃; for 0.25h;

diethylamine; In acetonitrile; at 0 - 20 ℃; for 0.666667h;
DOI:10.1021/ol400865b

Reference yield: 63.0%

: 2374-61-0
N,N-diethylmethanesulfonamide

: 108-90-7
chlorobenzene

: 62162-78-1
N,N-diethyl-1-phenylmethanesulfonamide

Guidance literature:: With N-(dicyclohexylphosphino)-2-(2'-methylphenyl)-1H-indole; [Pd{κ²N2′,C1-2-(2′-NH₂C₆H₄)C₆H₄}(μ-Cl)]₂; lithium tert-butoxide; In toluene; at 110 ℃; for 24h; chemoselective reaction; Inert atmosphere; Sealed tube;
DOI:10.1002/adsc.201600090

Reference yield:

: 6921-34-2
benzylmagnesium chloride

: 62162-78-1
N,N-diethyl-1-phenylmethanesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1,4-diazabicyclo [2.2.2] octane-1,4-diium-1,4-disulfinate / tetrahydrofuran / 1 h / -40 °C / Inert atmosphere

1.2: -40 - 20 °C / Inert atmosphere

2.1: tetrahydrofuran / 3 h / 20 °C / Inert atmosphere

With 1,4-diazabicyclo [2.2.2] octane-1,4-diium-1,4-disulfinate; In tetrahydrofuran;
DOI:10.1021/ol201957n