Technology Process of N,N-diethyl-1-phenylmethanesulfonamide
There total 5 articles about N,N-diethyl-1-phenylmethanesulfonamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
dibenzyl disulphide;
With
tert-butylhypochlorite; water;
In
acetonitrile;
at 0 ℃;
for 0.25h;
diethylamine;
In
acetonitrile;
at 0 - 20 ℃;
for 0.666667h;
DOI:10.1021/ol400865b
- Guidance literature:
-
With
N-(dicyclohexylphosphino)-2-(2'-methylphenyl)-1H-indole; [Pd{κ2N2′,C1-2-(2′-NH2C6H4)C6H4}(μ-Cl)]2; lithium tert-butoxide;
In
toluene;
at 110 ℃;
for 24h;
chemoselective reaction;
Inert atmosphere;
Sealed tube;
DOI:10.1002/adsc.201600090
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1,4-diazabicyclo [2.2.2] octane-1,4-diium-1,4-disulfinate / tetrahydrofuran / 1 h / -40 °C / Inert atmosphere
1.2: -40 - 20 °C / Inert atmosphere
2.1: tetrahydrofuran / 3 h / 20 °C / Inert atmosphere
With
1,4-diazabicyclo [2.2.2] octane-1,4-diium-1,4-disulfinate;
In
tetrahydrofuran;
DOI:10.1021/ol201957n