N-4-Phenyl a-Benzylidene-d5 Isobutyrylacetamide

Base Information

Chemical Name:N-4-Phenyl a-Benzylidene-d5 Isobutyrylacetamide
CAS No.:265989-32-0
Molecular Formula:C₁₉H₁₉NO₂
Molecular Weight:298.326
Hs Code.:
Mol file:265989-32-0.mol

Synonyms:N-4-Phenyl a-Benzylidene-d5 Isobutyrylacetamide;N-4-Phenyl α-Benzylidene-d5 Isobutyrylacetamide

Suppliers and Price of N-4-Phenyl a-Benzylidene-d5 Isobutyrylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Isobutyryl-N-phenyl-3-phenylacrylamide
5mg
$ 165.00

Medical Isotopes, Inc.
N-4-Phenylα-Benzylidene-d5Isobutyrylacetamide
5 mg
$ 890.00

Total 3 raw suppliers

Chemical Property of N-4-Phenyl a-Benzylidene-d5 Isobutyrylacetamide

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.622
Boiling Point:519.438°C at 760 mmHg
Flash Point:188.668°C
PSA：46.17000
Density:1.172g/cm³
LogP:3.25040
Solubility.:Acetone, Chloroform, Dichloromethane, Ethyl Acetate

Purity/Quality:

97% ^*data from raw suppliers

2-Isobutyryl-N-phenyl-3-phenylacrylamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses An deuterated intermediate of deuterated Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholestero l and triglycerides in patients with hypercholesterolemia.

Technology Process of N-4-Phenyl a-Benzylidene-d5 Isobutyrylacetamide

There total 3 articles about N-4-Phenyl a-Benzylidene-d5 Isobutyrylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4165-61-1
aniline-d5

: 265989-32-0
C₁₉H₁₄⁽²⁾H₅NO₂

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / toluene / 4 h / 80 °C

2: 15.26 g / β-alanine; glacial acetic acid / hexane / 25 h / Heating

With acetic acid; 3-amino propanoic acid; In hexane; toluene; 1: Acylation / 2: Condensation;
DOI:10.1002/(SICI)1099-1344(20000315)43:3<261::AID-JLCR312>3.0.CO;2-T

Reference yield:

: isobutyryl Meldrum's acid

: 265989-32-0
C₁₉H₁₄⁽²⁾H₅NO₂

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / toluene / 4 h / 80 °C

2: 15.26 g / β-alanine; glacial acetic acid / hexane / 25 h / Heating

With acetic acid; 3-amino propanoic acid; In hexane; toluene; 1: Acylation / 2: Condensation;
DOI:10.1002/(SICI)1099-1344(20000315)43:3<261::AID-JLCR312>3.0.CO;2-T

Reference yield:

: 100-52-7
benzaldehyde

: 265989-29-5
N-d5-phenyl isobutyrylacetamide

: 265989-32-0
C₁₉H₁₄⁽²⁾H₅NO₂

Guidance literature:: With acetic acid; 3-amino propanoic acid; In hexane; for 25h; Heating;
DOI:10.1002/(SICI)1099-1344(20000315)43:3<261::AID-JLCR312>3.0.CO;2-T