Methyl 1-[4-(1,1-dimethylethyl)phenyl]-5-oxo-3-pyrrolidinecarboxylate

Base Information

Chemical Name:Methyl 1-[4-(1,1-dimethylethyl)phenyl]-5-oxo-3-pyrrolidinecarboxylate
CAS No.:133747-82-7
Molecular Formula:C₁₆H₂₁NO₃
Molecular Weight:275.348
Hs Code.:
DSSTox Substance ID:DTXSID001157614

Synonyms:SCHEMBL6268227;DTXSID001157614;Methyl 1-[4-(1,1-dimethylethyl)phenyl]-5-oxo-3-pyrrolidinecarboxylate;133747-82-7

Suppliers and Price of Methyl 1-[4-(1,1-dimethylethyl)phenyl]-5-oxo-3-pyrrolidinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl 1-[4-(1,1-dimethylethyl)phenyl]-5-oxo-3-pyrrolidinecarboxylate

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:275.15214353
Heavy Atom Count:20
Complexity:378

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C1=CC=C(C=C1)N2CC(CC2=O)C(=O)OC

Technology Process of Methyl 1-[4-(1,1-dimethylethyl)phenyl]-5-oxo-3-pyrrolidinecarboxylate

There total 4 articles about Methyl 1-[4-(1,1-dimethylethyl)phenyl]-5-oxo-3-pyrrolidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.4%

: 67-56-1
methanol

: 133747-81-6
(+/-)-1-(4-tert-butylphenyl)-2-oxo-pyrrolidine-4-carboxylic acid

: 133747-82-7
methyl 1-(4-t-butylphenyl)-5-oxo-pyrrolidine-3-carboxylate

Guidance literature:: With sulfuric acid; In dichloromethane; for 14h; Heating;
DOI:10.1016/0223-5234(94)90029-9

Reference yield:

: 97-65-4,25119-64-6
2-methylenesuccinic acid

: 133747-82-7
methyl 1-(4-t-butylphenyl)-5-oxo-pyrrolidine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 95.1 percent / Heating

2: 98.4 percent / conc. H₂SO₄ / CH₂Cl₂ / 14 h / Heating

With sulfuric acid; In dichloromethane;
DOI:10.1016/0223-5234(94)90029-9

Reference yield:

: 769-92-6
4-tert-Butylaniline

: 133747-82-7
methyl 1-(4-t-butylphenyl)-5-oxo-pyrrolidine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 95.1 percent / Heating

2: 98.4 percent / conc. H₂SO₄ / CH₂Cl₂ / 14 h / Heating

With sulfuric acid; In dichloromethane;
DOI:10.1016/0223-5234(94)90029-9