[4-(dibenzothien-2-yl)-2-mercapto-6-phenyl-1,6-dihydropyrimidin-5-yl]acetic acid

Base Information

• Chemical Name: [4-(dibenzothien-2-yl)-2-mercapto-6-phenyl-1,6-dihydropyrimidin-5-yl]acetic acid
• CAS No.: 1055874-85-5
• Molecular Formula: C₂₄H₁₈N₂O₂S₂
• Molecular Weight: 430.551
• Mol file: 1055874-85-5.mol

Synonyms:[4-(dibenzothien-2-yl)-2-mercapto-6-phenyl-1,6-dihydropyrimidin-5-yl]acetic acid

Chemical Property of [4-(dibenzothien-2-yl)-2-mercapto-6-phenyl-1,6-dihydropyrimidin-5-yl]acetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [4-(dibenzothien-2-yl)-2-mercapto-6-phenyl-1,6-dihydropyrimidin-5-yl]acetic acid

There total 1 articles about [4-(dibenzothien-2-yl)-2-mercapto-6-phenyl-1,6-dihydropyrimidin-5-yl]acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

β-(dibenzothiophene-2-carbonyl)propionic acid (88878-79-9) + benzaldehyde (100-52-7) + thiourea (17356-08-0) → [4-(dibenzothien-2-yl)-2-mercapto-6-phenyl-1,6-dihydropyrimidin-5-yl]acetic acid (1055874-85-5)

Guidance literature:

With potassium carbonate; In ethanol; for 10h; Heating;

DOI:10.3184/030823407X248621

Reference yield: 75.0%

[4-(dibenzothien-2-yl)-2-mercapto-6-phenyl-1,6-dihydropyrimidin-5-yl]acetic acid (1055874-85-5) + chloroacetic acid (79-11-8) → [7-(dibenzothien-2-yl)-3-oxo-5-phenyl-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-6-yl]acetic acid

Guidance literature:

With sodium acetate; In acetic anhydride; acetic acid; for 4h; Heating;

DOI:10.3184/030823407X248621 DOI:10.1002/jhet.5570450408

Reference yield: 74.0%

[4-(dibenzothien-2-yl)-2-mercapto-6-phenyl-1,6-dihydropyrimidin-5-yl]acetic acid (1055874-85-5) + ethylene dibromide (106-93-4) → [7-(dibenzothien-2-yl)-5-phenyl-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-6-yl]acetic acid

Guidance literature:

With sodium hydroxide; In N,N-dimethyl-formamide; for 2h; Heating;

DOI:10.3184/030823407X248621 DOI:10.1002/jhet.5570450408

upstream raw materials:

β-(dibenzothiophene-2-carbonyl)propionic acid

benzaldehyde

thiourea