3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetaldehyde

Base Information

Chemical Name:3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetaldehyde
CAS No.:582289-85-8
Molecular Formula:C₁₈H₂₄O₅
Molecular Weight:320.386
Hs Code.:
Mol file:582289-85-8.mol

Synonyms:3,4-bis(tetrahydropyran-2-yloxy)phenylacetaldehyde

Suppliers and Price of 3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetaldehyde
250mg
$ 195.00

TRC
3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetaldehyde
2.5g
$ 1540.00

Medical Isotopes, Inc.
3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetaldehyde
250 mg
$ 675.00

Total 1 raw suppliers

Chemical Property of 3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetaldehyde

Chemical Property:

Boiling Point:479.1±45.0 °C(Predicted)
Density:1.166±0.06 g/cm3(Predicted)

Purity/Quality:: 3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetaldehyde is an intermediate in the synthesis of Dopal (D533885), the reactive metabolite of dopamine (D533780), an endogenous catecholamine with α and β-adrenergic activity.

Technology Process of 3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetaldehyde

There total 4 articles about 3,4-Bis[(tetrahydro-2H-pyran-2-yl)oxy]benzeneacetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 582289-84-7
3,4-bis(tetrahydropyran-2-yloxy)phenylacetic acid methyl ester

: 582289-85-8
3,4-bis(tetrahydropyran-2-yloxy)phenylacetaldehyde

Guidance literature:: With diisobutylaluminium hydride; In toluene; at -78 ℃; for 0.5h;
DOI:10.1016/S0045-2068(03)00019-1

Reference yield:

: C₁₈H₂₆O₅

: 582289-85-8
3,4-bis(tetrahydropyran-2-yloxy)phenylacetaldehyde

Guidance literature:: With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1248/CPB.C20-00294

Reference yield:

: 102-32-9
3,4-dihydroxyphenylacetate

: 582289-85-8
3,4-bis(tetrahydropyran-2-yloxy)phenylacetaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: conc. H₂SO₄ / Heating

2: pyridinium p-tosylate / CH₂Cl₂ / 1 h

3: 52 percent / DIBALH / toluene / 0.5 h / -78 °C

With sulfuric acid; pyridinium p-toluenesulfonate; diisobutylaluminium hydride; In dichloromethane; toluene;
DOI:10.1016/S0045-2068(03)00019-1