3,4-Dihydroxyphenylacetaldehyde

Base Information

Chemical Name:3,4-Dihydroxyphenylacetaldehyde
CAS No.:5707-55-1
Molecular Formula:C8H8 O3
Molecular Weight:152.15
Hs Code.:
European Community (EC) Number:809-292-1
UNII:F2E9Q24TSL
DSSTox Substance ID:DTXSID10205680
Nikkaji Number:J466.586D
Wikipedia:3,4-Dihydroxyphenylacetaldehyde
Wikidata:Q4634065
Metabolomics Workbench ID:38395
Mol file:5707-55-1.mol

Synonyms:3,4-dihydroxyphenylacetaldehyde;DHPAA aldehyde

Suppliers and Price of 3,4-Dihydroxyphenylacetaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Dopal(>80%)
25mg
$ 165.00

Medical Isotopes, Inc.
Dopal(>80%)
2.5 mg
$ 650.00

Cayman Chemical
DOPAL ≥95%
10mg
$ 74.00

Cayman Chemical
DOPAL ≥95%
5mg
$ 39.00

Cayman Chemical
DOPAL ≥95%
50mg
$ 303.00

Cayman Chemical
DOPAL ≥95%
25mg
$ 171.00

American Custom Chemicals Corporation
3,4-DIHYDROXY-A-TOLUALDEHYDE 95.00%
5MG
$ 504.59

AK Scientific
3,4-Dihydroxyphenylacetaldehyde
5mg
$ 147.00

Total 14 raw suppliers

Chemical Property of 3,4-Dihydroxyphenylacetaldehyde

Chemical Property:

Vapor Pressure:2.11E-05mmHg at 25°C
Boiling Point:350.9°Cat760mmHg
PKA:9.62±0.10(Predicted)
Flash Point:180.2°C
PSA：57.53000
Density:1.306g/cm³
LogP:0.83920
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:152.047344113
Heavy Atom Count:11
Complexity:135

Purity/Quality:

99%, ^*data from raw suppliers

Dopal(>80%) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1CC=O)O)O
General Description 2-(3,4-Dihydroxyphenyl)acetaldehyde, also known as DOPAL, is a neurotoxic aldehyde derived from dopamine metabolism via monoamine oxidase activity. It serves as a key intermediate in the formation of dopamine metabolites such as 3,4-dihydroxyphenylacetic acid and homovanillic acid. DOPAL has been implicated in neurodegenerative diseases like Parkinson's and Alzheimer's due to its cytotoxic effects, and its synthesis and biochemical properties are of significant research interest. Additionally, structurally related compounds, such as 3,4-dihydroxystyrene dimers, exhibit biological activity in marine organisms but are distinct from DOPAL's neurochemical role.

Technology Process of 3,4-Dihydroxyphenylacetaldehyde

There total 22 articles about 3,4-Dihydroxyphenylacetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 51-61-6
dopamine

: 5707-55-1
3,4-Dihydroxyphenylacetaldehyde

Guidance literature:: With Halomonas elongata/Co imm pyridoxal phosphate; In toluene; at 37 ℃; for 0.25h; pH=7.5; Flow reactor; Enzymatic reaction;
DOI:10.1002/cbic.201900356

Reference yield: 50.0%

: 582289-85-8
3,4-bis(tetrahydropyran-2-yloxy)phenylacetaldehyde

: 5707-55-1
3,4-Dihydroxyphenylacetaldehyde

Guidance literature:: With Amberlite-H⁺; In tetrahydrofuran; water; for 4h;
DOI:10.1016/S0045-2068(03)00019-1

Reference yield: 44.0%

: 10597-60-1
hydroxytyrosol

: 5707-55-1
3,4-Dihydroxyphenylacetaldehyde

Guidance literature:: With sulfur trioxide pyridine complex; N-ethyl-N,N-diisopropylamine; In dichloromethane; dimethyl sulfoxide; at -15 ℃; for 1.5h;
DOI:10.1021/acs.orglett.1c03320