Technology Process of C19H26O4
There total 5 articles about C19H26O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(E)-3-((2R,7R)-7-((S)-1-(benzyloxy)propyl)-2,3,6,7-tetrahydrooxepin-2-yl)prop-2-en-1-ol;
With
titanium(IV) isopropylate; diethyl (2R,3R)-tartrate;
In
dichloromethane;
at -20 ℃;
for 0.5h;
Molecular sieve;
With
tert.-butylhydroperoxide; tartaric acid;
In
dichloromethane; water;
at 20 ℃;
for 8h;
Molecular sieve;
DOI:10.1039/c4cc00389f
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride; tetra-(n-butyl)ammonium iodide / tetrahydrofuran; mineral oil / 0 - 70 °C / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -20 °C / Inert atmosphere
2.2: 20 °C / Inert atmosphere
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 20 °C / Inert atmosphere
4.1: diethyl (2R,3R)-tartrate; titanium(IV) isopropylate / dichloromethane / 0.5 h / -20 °C / Molecular sieve
4.2: 8 h / 20 °C / Molecular sieve
With
titanium(IV) isopropylate; lithium aluminium tetrahydride; n-butyllithium; diethyl (2R,3R)-tartrate; tetra-(n-butyl)ammonium iodide; sodium hydride;
In
tetrahydrofuran; hexane; dichloromethane; mineral oil;
DOI:10.1039/c4cc00389f
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 20 °C / Inert atmosphere
2.1: diethyl (2R,3R)-tartrate; titanium(IV) isopropylate / dichloromethane / 0.5 h / -20 °C / Molecular sieve
2.2: 8 h / 20 °C / Molecular sieve
With
titanium(IV) isopropylate; lithium aluminium tetrahydride; diethyl (2R,3R)-tartrate;
In
tetrahydrofuran; dichloromethane;
DOI:10.1039/c4cc00389f
