C₅Me₄HC₆H₄OMe-4

Base Information

• Chemical Name: C₅Me₄HC₆H₄OMe-4
• CAS No.: 329258-12-0
• Molecular Formula: C₁₆H₂₀O
• Molecular Weight: 228.334
• Mol file: 329258-12-0.mol

Synonyms:C₅Me₄HC₆H₄OMe-4

Chemical Property of C₅Me₄HC₆H₄OMe-4

Chemical Property:

Purity/Quality:

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Technology Process of C₅Me₄HC₆H₄OMe-4

There total 1 articles about C₅Me₄HC₆H₄OMe-4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

(2Z,4E)-2-Iodo-3,4-dimethyl-hexa-2,4-diene + 4-methoxy-benzaldehyde (123-11-5) → C5Me4HC6H4OMe-4 (329258-12-0)

Guidance literature:

(2Z,4E)-2-Iodo-3,4-dimethyl-hexa-2,4-diene; With tert.-butyl lithium; In diethyl ether; pentane; at -78 ℃; for 1h;

4-methoxy-benzaldehyde; In diethyl ether; pentane; at -78 ℃; for 0.5h;

With hydrogenchloride; In diethyl ether; water; pentane;

DOI:10.1016/j.tet.2006.04.083

Reference yield: 46.0%

C5Me4HC6H4OMe-4 (329258-12-0) + n-butyllithium (109-72-8,29786-93-4) + lithium cyclopentadienide + zirconium(IV) chloride (10026-11-6) → (C5(CH3)4(C6H4)OCH3)(C5H5)ZrCl2 (329258-14-2)

Guidance literature:

With hydrogenchloride; dichloromethane; In hexane; toluene; under Ar; mixt. of n-BuLi/hexane and C5Me4HC6H4OMe-4/toluene stirred overnight at room temp.; ZrCl4 added; refluxed for 24 h; CpLi added; refluxed for 24 h; solvents removed; CH2Cl2 and HCl (6 N) added to residue; org. phase sepd.; washed (H2O), dried (Na2SO4); concd. hexane added; crystd.; elem. anal.;

DOI:10.1016/S1381-1169(02)00036-5

upstream raw materials:

4-methoxy-benzaldehyde

Downstream raw materials:

(C₅(CH₃)4(C₆H₄)OCH₃)(C₅H₅)ZrCl₂