4-(3-Fluorophenoxy)piperidine

Base Information

Chemical Name:4-(3-Fluorophenoxy)piperidine
CAS No.:3202-35-5
Molecular Formula:C11H14 F N O
Molecular Weight:195.237
Hs Code.:2933399090
DSSTox Substance ID:DTXSID20594436
Wikidata:Q82489264
Mol file:3202-35-5.mol

Synonyms:4-(3-Fluorophenoxy)piperidine;3202-35-5;4-(3-Fluoro-phenoxy)-piperidine;Piperidine,4-(3-fluorophenoxy)-;SCHEMBL254980;DTXSID20594436;ADUCMSHWWWCKEK-UHFFFAOYSA-N;4-[(3-Fluorophenyl)oxy]piperidine;MFCD06247708;AKOS000192574;SB41830;BS-33466;CS-0208344;EN300-241653

Suppliers and Price of 4-(3-Fluorophenoxy)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-(3-Fluorophenoxy)piperidine 95+%
5g
$ 874.00

Chemenu
4-(3-Fluorophenoxy)piperidine 95%
5g
$ 825.00

ChemBridge Corporation
4-(3-fluorophenoxy)piperidine 95%
1 g
$ 235.00

ChemBridge Corporation
4-(3-fluorophenoxy)piperidine 95%
250 mg
$ 121.00

American Custom Chemicals Corporation
4-(3-FLUOROPHENOXY)PIPERIDINE 95.00%
10G
$ 3122.84

American Custom Chemicals Corporation
4-(3-FLUOROPHENOXY)PIPERIDINE 95.00%
5G
$ 1976.78

American Custom Chemicals Corporation
4-(3-FLUOROPHENOXY)PIPERIDINE 95.00%
1G
$ 952.01

Total 8 raw suppliers

Chemical Property of 4-(3-Fluorophenoxy)piperidine

Chemical Property:

Vapor Pressure:0.00686mmHg at 25°C
Refractive Index:1.51
Boiling Point:270.4°C at 760 mmHg
PKA:9.68±0.10(Predicted)
Flash Point:117.3°C
PSA：21.26000
Density:1.108g/cm³
LogP:2.28530
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:195.105942232
Heavy Atom Count:14
Complexity:171

Purity/Quality:

97% ^*data from raw suppliers

4-(3-Fluorophenoxy)piperidine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1OC2=CC(=CC=C2)F

Technology Process of 4-(3-Fluorophenoxy)piperidine

There total 4 articles about 4-(3-Fluorophenoxy)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 920511-29-1
1,1-dimethylethyl 4-((3-fluorophenyl)oxy)-1-piperidinecarboxylate

: 3202-35-5
4-(3-fluorophenoxy)piperidine

Guidance literature:: 1,1-dimethylethyl 4-((3-fluorophenyl)oxy)-1-piperidinecarboxylate; With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 2.5h;

With sodium hydroxide; In dichloromethane; water;

Reference yield:

: 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate

: 3202-35-5
4-(3-fluorophenoxy)piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 5 h / 20 °C

2: trifluoroacetic acid / dichloromethane / 20 °C

With triphenylphosphine; trifluoroacetic acid; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane;
DOI:10.1039/c8ra00720a

Reference yield:

: 372-20-3
3-fluorophenol

: 3202-35-5
4-(3-fluorophenoxy)piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 5 h / 20 °C

2: trifluoroacetic acid / dichloromethane / 20 °C

With triphenylphosphine; trifluoroacetic acid; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane;
DOI:10.1039/c8ra00720a