phenyl cyclobut-1-ene-1-carboxylate

Base Information

• Chemical Name: phenyl cyclobut-1-ene-1-carboxylate
• CAS No.: 1131864-90-8
• Molecular Formula: C₁₁H₁₀O₂
• Molecular Weight: 174.199
• Mol file: 1131864-90-8.mol

Synonyms:phenyl cyclobut-1-ene-1-carboxylate

Chemical Property of phenyl cyclobut-1-ene-1-carboxylate

Chemical Property:

Purity/Quality:

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Technology Process of phenyl cyclobut-1-ene-1-carboxylate

There total 6 articles about phenyl cyclobut-1-ene-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

1-cyclobutenecarboxylic acid (23519-90-6) + phenol (108-95-2,27073-41-2) → phenyl cyclobut-1-ene-1-carboxylate (1131864-90-8)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1021/jacs.9b13071

Reference yield: 47.0%

oxalyl dichloride (79-37-8) + 1-cyclobutenecarboxylic acid (23519-90-6) + phenol (108-95-2,27073-41-2) → phenyl cyclobut-1-ene-1-carboxylate (1131864-90-8)

Guidance literature:

With hydrogenchloride; triethylamine; In dichloromethane;

Reference yield:

1-cyclobutenecarboxylic acid chloride + phenol (108-95-2,27073-41-2) → phenyl cyclobut-1-ene-1-carboxylate (1131864-90-8)

Guidance literature:

phenol; With triethylamine; In dichloromethane; at 0 ℃; for 1h;

1-cyclobutenecarboxylic acid chloride; In dichloromethane; at 20 ℃; for 16h;

DOI:10.1021/ja809661k

upstream raw materials:

phenol

oxalyl dichloride

1-cyclobutenecarboxylic acid

ethyl 1-bromocyclobutane-1-carboxylate