methyl 2-hydroxyphenylcarbamate

Base Information

• Chemical Name: methyl 2-hydroxyphenylcarbamate
• CAS No.: 40783-78-6
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.164
• Mol file: 40783-78-6.mol

Synonyms:carbamate de methyle et de N(hydroxy-2 phenyle)

Chemical Property of methyl 2-hydroxyphenylcarbamate

Chemical Property:

Purity/Quality:

METHYL N-(2-HYDROXYPHENYL)CARBAMATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-hydroxyphenylcarbamate

There total 8 articles about methyl 2-hydroxyphenylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

methyl chloroformate (79-22-1) + 2-amino-phenol (95-55-6) → carbamate de methyle et de N(hydroxy-2 phenyle) (40783-78-6)

Guidance literature:

With indium; In acetonitrile; at 20 ℃; for 10h; chemoselective reaction; Inert atmosphere;

DOI:10.1016/j.tetlet.2009.03.143

Reference yield: 70.0%

methanol (67-56-1) + N(hydroxy-2 phenyl) carbamate de phenyle (41064-78-2) → carbamate de methyle et de N(hydroxy-2 phenyle) (40783-78-6)

Guidance literature:

methanol; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 0.5h; Inert atmosphere;

N(hydroxy-2 phenyl) carbamate de phenyle; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.0c03786

Reference yield: 41.0%

N-phenyl methyl carbamate (2603-10-3) → carbamate de methyle et de N(hydroxy-2 phenyle) (40783-78-6)

Guidance literature:

With sodium persulfate; palladium diacetate; In 1,4-dioxane; at 80 ℃; for 24h; Inert atmosphere;

DOI:10.1039/c4cc06864e

upstream raw materials:

methyl chloroformate

2-amino-phenol

methanol

C₁₃H₁₆N₂O₃