N-Methyl cyclobutylamine

Base Information

• Chemical Name: N-Methyl cyclobutylamine
• CAS No.: 34066-62-1
• Molecular Formula: C5H11 N
• Molecular Weight: 85.149
• Hs Code.: 2921300090
• Mol file: 34066-62-1.mol

Synonyms:Cyclobutylamine,N-methyl- (8CI); N-Cyclobutyl-N-methylamine; N-Methyl-N-(cyclobutyl)amine;N-Methylcyclobutanamine; N-Methylcyclobutylamine

Chemical Property of N-Methyl cyclobutylamine

Chemical Property:

• Boiling Point: 95.6±8.0 °C(Predicted)
• PKA: 10.94±0.20(Predicted)
• PSA: 12.03000
• Density: 0.84±0.1 g/cm3(Predicted)
• LogP: 1.14920

Purity/Quality:

97% ^*data from raw suppliers

N-methylcyclobutanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Methyl cyclobutylamine

There total 2 articles about N-Methyl cyclobutylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclobutanone (1191-95-3) + methylamine (74-89-5) → N-methylcyclobutanamine (34066-62-1)

Guidance literature:

With anhydrous methoxyethanol; Hydrogenation_.anschliessend Hydrierung an Platin;

DOI:10.1021/ja01180a013

Reference yield:

→ N-methylcyclobutanamine (34066-62-1)

Guidance literature:

Reference yield: 33.0%

2-N-[3-(3-chloropropoxy)-4-methoxyphenyl]-4-N,6-dimethylpyrimidine-2,4-diamine + N-methylcyclobutanamine (34066-62-1) → N2-(3-(3-(cyclobutyl(methyl)amino)propoxy)-4-methoxyphenyl)-N4,6-dimethylpyrimidine-2,4-diamine

Guidance literature:

With potassium carbonate; sodium iodide; In acetonitrile; at 85 ℃; for 10h;

upstream raw materials:

cyclobutanone

methylamine

Downstream raw materials:

C₂₈H₃₃N₅O₄

C₂₁H₃₂F₂N₂O

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