Trans-3,4-Bis(methylmethanethiosulfonylmethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl Radical

Base Information

• Chemical Name: Trans-3,4-Bis(methylmethanethiosulfonylmethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl Radical
• CAS No.: 229621-30-1
• Molecular Formula: C₁₂H₂₄NO₅S₄
• Molecular Weight: 390.59
• Mol file: 229621-30-1.mol

Synonyms:Trans-3,4-Bis(methylmethanethiosulfonylmethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl Radical

Chemical Property of Trans-3,4-Bis(methylmethanethiosulfonylmethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl Radical

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 103-104°C
• Refractive Index: 1.546
• Boiling Point: 606.045°C at 760 mmHg
• Flash Point: 320.325°C
• PSA: 138.88000
• Density: 1.311g/cm³
• LogP: 3.92220
• Storage Temp.: -20°C Freezer, Under Inert Atmosphere
• Solubility.: Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

Trans-3,4-Bis[[(methylsulfonyl)thio]methyl]-2,2,5,5-tetramethylpyrrolidin-1-yloxylRadical ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A cross-linking sulfhydryl spin label

Technology Process of Trans-3,4-Bis(methylmethanethiosulfonylmethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl Radical

There total 5 articles about Trans-3,4-Bis(methylmethanethiosulfonylmethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl Radical which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

sodium methanethiosulfonate (1950-85-2) + trans-3,4-Bis(iodomethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl radical (229621-29-8) → trans-3,4-Bis(methanesulfonylthiomethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl radical (229621-30-1)

Guidance literature:

In dimethyl sulfoxide; at 70 ℃; for 0.5h;

DOI:10.1055/s-1999-3502

Reference yield:

trans-3-methoxycarbonyl-2,2,5,5-tetramethyl-4-nitromethylpyrrolidin-1-oxyl (119580-75-5) → trans-3,4-Bis(methanesulfonylthiomethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl radical (229621-30-1)

Guidance literature:

Multi-step reaction with 5 steps

1: 1.) KOH, 2.) KMnO₄, MgSO₄ / 1.) MeOH, 0 deg C, 15 min, 2.) MeOH, H₂O, 0 deg C, 2 h

2: 80 percent / NaBH₄ / ethanol / 0.5 h / Ambient temperature

3: Et₃N / CH₂Cl₂ / 1 h / Ambient temperature

4: NaI / tetrahydrofuran / 48 h / Heating

5: 33 percent / dimethylsulfoxide / 0.5 h / 70 °C

With potassium hydroxide; sodium tetrahydroborate; potassium permanganate; magnesium sulfate; triethylamine; sodium iodide; In tetrahydrofuran; ethanol; dichloromethane; dimethyl sulfoxide;

DOI:10.1055/s-1999-3502

Reference yield:

trans-4-Formyl-3-methoxycarbonyl-2,2,5,5-tetramethylpyrrolidin-1-yloxyl radical (229621-04-9) → trans-3,4-Bis(methanesulfonylthiomethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl radical (229621-30-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 80 percent / NaBH₄ / ethanol / 0.5 h / Ambient temperature

2: Et₃N / CH₂Cl₂ / 1 h / Ambient temperature

3: NaI / tetrahydrofuran / 48 h / Heating

4: 33 percent / dimethylsulfoxide / 0.5 h / 70 °C

With sodium tetrahydroborate; triethylamine; sodium iodide; In tetrahydrofuran; ethanol; dichloromethane; dimethyl sulfoxide;

DOI:10.1055/s-1999-3502

upstream raw materials:

sodium methanethiosulfonate

trans-3,4-Bis(iodomethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl radical

trans-3-methoxycarbonyl-2,2,5,5-tetramethyl-4-nitromethylpyrrolidin-1-oxyl

trans-4-Formyl-3-methoxycarbonyl-2,2,5,5-tetramethylpyrrolidin-1-yloxyl radical

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 229621-30-1 Trans-3,4-Bis(methylmethanethiosulfonylmethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl Radical

Send

Send

Metric Ton KG G Pound L ML

Send

Send