(3R,4R)-rel-3,4-Bis(iodomethyl)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy

Base Information

Chemical Name:(3R,4R)-rel-3,4-Bis(iodomethyl)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy
CAS No.:229621-29-8
Molecular Formula:C10H18I2NO
Molecular Weight:422.06500
Hs Code.:
DSSTox Substance ID:DTXSID30573095
Mol file:229621-29-8.mol

Synonyms:229621-29-8;(3R,4R)-rel-3,4-Bis(iodomethyl)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy;(3R,4R)-1-hydroxy-3,4-bis(iodomethyl)-2,2,5,5-tetramethylpyrrolidine;DTXSID30573095;(3R,4R)-3,4-Bis(iodomethyl)-2,2,5,5-tetramethylpyrrolidin-1-ol

Suppliers and Price of (3R,4R)-rel-3,4-Bis(iodomethyl)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3R,4R)-rel-3,4-Bis(iodomethyl)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy
2.5mg
$ 165.00

Total 2 raw suppliers

Chemical Property of (3R,4R)-rel-3,4-Bis(iodomethyl)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy

Chemical Property:

PSA：3.24000
LogP:3.24500
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:422.95561
Heavy Atom Count:14
Complexity:196

Purity/Quality:

95% ^*data from raw suppliers

(3R,4R)-rel-3,4-Bis(iodomethyl)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(C(C(N1O)(C)C)CI)CI)C
Isomeric SMILES:CC1([C@@H]([C@H](C(N1O)(C)C)CI)CI)C
Uses (3R,4R)-rel-3,4-Bis(iodoMethyl)-2,2,5,5-tetraMethyl-1-pyrrolidinyloxy is a bis-iodomethyl nitroxide compound used in the development of conducting-magnetic bifunctional materials.

Technology Process of (3R,4R)-rel-3,4-Bis(iodomethyl)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy

There total 4 articles about (3R,4R)-rel-3,4-Bis(iodomethyl)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₂H₂₄NO₇S₂

: 229621-29-8
trans-3,4-Bis(iodomethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl radical

Guidance literature:: With sodium iodide; In tetrahydrofuran; for 48h; Yield given; Heating;
DOI:10.1055/s-1999-3502

Reference yield:

: 119580-75-5
trans-3-methoxycarbonyl-2,2,5,5-tetramethyl-4-nitromethylpyrrolidin-1-oxyl

: 229621-29-8
trans-3,4-Bis(iodomethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl radical

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) KOH, 2.) KMnO₄, MgSO₄ / 1.) MeOH, 0 deg C, 15 min, 2.) MeOH, H₂O, 0 deg C, 2 h

2: 80 percent / NaBH₄ / ethanol / 0.5 h / Ambient temperature

3: Et₃N / CH₂Cl₂ / 1 h / Ambient temperature

4: NaI / tetrahydrofuran / 48 h / Heating

With potassium hydroxide; sodium tetrahydroborate; potassium permanganate; magnesium sulfate; triethylamine; sodium iodide; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1055/s-1999-3502

Reference yield:

: 229621-04-9
trans-4-Formyl-3-methoxycarbonyl-2,2,5,5-tetramethylpyrrolidin-1-yloxyl radical

: 229621-29-8
trans-3,4-Bis(iodomethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl radical

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / NaBH₄ / ethanol / 0.5 h / Ambient temperature

2: Et₃N / CH₂Cl₂ / 1 h / Ambient temperature

3: NaI / tetrahydrofuran / 48 h / Heating

With sodium tetrahydroborate; triethylamine; sodium iodide; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1055/s-1999-3502