O-(2R,3S,4S)-2-((4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-4-methyldecan-3-yl (S)-methyl carbonodithioate

Base Information

Chemical Name:O-(2R,3S,4S)-2-((4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-4-methyldecan-3-yl (S)-methyl carbonodithioate
CAS No.:1453811-64-7
Molecular Formula:C₂₅H₄₀O₄S₂
Molecular Weight:468.722
Hs Code.:

Synonyms:O-(2R,3S,4S)-2-((4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-4-methyldecan-3-yl (S)-methyl carbonodithioate

Suppliers and Price of O-(2R,3S,4S)-2-((4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-4-methyldecan-3-yl (S)-methyl carbonodithioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of O-(2R,3S,4S)-2-((4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-4-methyldecan-3-yl (S)-methyl carbonodithioate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of O-(2R,3S,4S)-2-((4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-4-methyldecan-3-yl (S)-methyl carbonodithioate

There total 5 articles about O-(2R,3S,4S)-2-((4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-4-methyldecan-3-yl (S)-methyl carbonodithioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 75-15-0,12122-00-8
carbon disulfide

: 1453811-60-3
(2S,3S,4S)-2-((4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-4-methyldecan-3-ol

: 74-88-4
methyl iodide

: 1453811-64-7
O-(2R,3S,4S)-2-((4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-4-methyldecan-3-yl (S)-methyl carbonodithioate

Guidance literature:: (2S,3S,4S)-2-((4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-4-methyldecan-3-ol; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.5h;

carbon disulfide; In tetrahydrofuran; at -78 ℃; for 0.5h;

methyl iodide; In tetrahydrofuran; at -78 ℃; for 0.0833333h;
DOI:10.1016/j.tetasy.2013.07.012

Reference yield:

: 7786-29-0,49642-49-1,72598-55-1,55352-42-6
(S)-α-methyloctanal

: 1453811-64-7
O-(2R,3S,4S)-2-((4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-4-methyldecan-3-yl (S)-methyl carbonodithioate

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylamine; dicyclohexylboron chloride / diethyl ether / 2.5 h / -78 - 0 °C

1.2: -78 - 0 °C

2.1: tetramethylammonium triacetoxyborohydride / acetone; acetic acid / 30 h / -20 °C

3.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 0.5 h / 0 °C / Molecular sieve

4.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 °C

4.2: 0.5 h / -78 °C

4.3: 0.08 h / -78 °C

With dicyclohexylboron chloride; sodium hexamethyldisilazane; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; tetramethylammonium triacetoxyborohydride; In tetrahydrofuran; diethyl ether; dichloromethane; acetic acid; acetone;
DOI:10.1016/j.tetasy.2013.07.012

Reference yield:

: 1453811-61-4
(2S,4S,5S,6S)-5-hydroxy-1-(4-methoxybenzyloxy)-2,4,6-trimethyldodecan-3-one

: 1453811-64-7
O-(2R,3S,4S)-2-((4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl)-4-methyldecan-3-yl (S)-methyl carbonodithioate

Guidance literature:: Multi-step reaction with 3 steps

1.1: tetramethylammonium triacetoxyborohydride / acetone; acetic acid / 30 h / -20 °C

2.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 0.5 h / 0 °C / Molecular sieve

3.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 °C

3.2: 0.5 h / -78 °C

3.3: 0.08 h / -78 °C

With sodium hexamethyldisilazane; 2,3-dicyano-5,6-dichloro-p-benzoquinone; tetramethylammonium triacetoxyborohydride; In tetrahydrofuran; dichloromethane; acetic acid; acetone;
DOI:10.1016/j.tetasy.2013.07.012