Methyl (2R,3S)-3--L-histidyl>amino-2-hydroxy-5-methylhexanoate

Base Information

Chemical Name:Methyl (2R,3S)-3--L-histidyl>amino-2-hydroxy-5-methylhexanoate
CAS No.:132561-47-8
Molecular Formula:C₃₇H₄₅N₅O₆
Molecular Weight:655.794
Hs Code.:

Methyl (2R,3S)-3-<N-<(2R)-2-(1-Naphthylmethyl)-3-(N-phenethylcarbamoyl)propionyl>-L-histidyl>amino-2-hydroxy-5-methylhexanoate

Synonyms:Methyl (2R,3S)-3--L-histidyl>amino-2-hydroxy-5-methylhexanoate

Suppliers and Price of Methyl (2R,3S)-3--L-histidyl>amino-2-hydroxy-5-methylhexanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl (2R,3S)-3--L-histidyl>amino-2-hydroxy-5-methylhexanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methyl (2R,3S)-3--L-histidyl>amino-2-hydroxy-5-methylhexanoate

There total 6 articles about Methyl (2R,3S)-3--L-histidyl>amino-2-hydroxy-5-methylhexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 105166-78-7,106868-71-7,106868-80-8
Methyl (2RS,3S)-3-Amino-2-hydroxy-5-methylhexanoate Hydrochloride

: (S)-3-(1H-Imidazol-4-yl)-2-[(R)-3-naphthalen-1-yl-2-(phenethylcarbamoyl-methyl)-propionylamino]-propionyl azide

: 132561-47-8
Methyl (2R,3S)-3--L-histidyl>amino-2-hydroxy-5-methylhexanoate

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 0 ℃; for 16h;
DOI:10.1248/cpb.38.3042

Reference yield:

: 5.1N-hydrogen chloride

: 341973-08-8
(3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Methyl Ester Hydrochloride

: 144-55-8
sodium hydrogencarbonate

: 103633-21-2
N-[(+/-)-2-(1-naphthylmethyl)3-(phenethylcarbamoyl)propionyl]-L-histidine hydrazide

: N-[(+/-)-2-(1-naphthylmethyl)-3-(phenethylcarbamoyl)propionyl]-L-histidine azide

: 110-46-3
isopentyl nitrite

: 105186-68-3,132561-47-8
Methyl (3S)-3-{N-[(+)-2-(1-naphthylmethyl)-3-(phenethylcarbamoyl)propionyl]-L-histidyl}amino-2-hydroxy-5-methylhexanoate

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide;

Reference yield:

: 132488-68-7
N-<(2R)-2-(1-naphthylmethyl)-3-(N-phenethylcarbamoyl)propionyl>-L-histidine methyl ester

: 132561-47-8
Methyl (2R,3S)-3--L-histidyl>amino-2-hydroxy-5-methylhexanoate

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / hydrazine hydrate / methanol / overnight

2: isoamyl nitrite

3: 34 percent / Et₃N / dimethylformamide / 16 h / 0 °C

With hydrazine hydrate; triethylamine; isopentyl nitrite; In methanol; N,N-dimethyl-formamide;
DOI:10.1248/cpb.38.3042