(3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Methyl Ester Hydrochloride

Base Information

• Chemical Name: (3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Methyl Ester Hydrochloride
• CAS No.: 341973-08-8
• Molecular Formula: C₈H₁₇NO₃*ClH
• Molecular Weight: 211.689

Synonyms:(3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Methyl Ester Hydrochloride

Chemical Property of (3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Methyl Ester Hydrochloride

Chemical Property:

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Technology Process of (3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Methyl Ester Hydrochloride

There total 7 articles about (3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Methyl Ester Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + (3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Hydrochloride (341973-07-7) → (3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Methyl Ester Hydrochloride (341973-08-8)

Guidance literature:

With thionyl chloride; at -40 - 20 ℃; for 4.16667h;

Reference yield:

(3S)-3-(N-t-butoxycarbonylamino)-2-hydroxy-5-methylhexanoic Acid Methyl Ester (318464-23-2) → (3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Methyl Ester Hydrochloride (341973-08-8)

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 20 ℃; for 0.666667h;

Reference yield:

(3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Hydrochloride (341973-07-7) → (3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Methyl Ester Hydrochloride (341973-08-8)

Guidance literature:

With thionyl chloride; In methanol;

upstream raw materials:

(3S)-3-amino-2-hydroxy-5-methylhexanoic Acid Hydrochloride

(3S)-3-(N-t-butoxycarbonylamino)-2-hydroxy-5-methylhexanoic Acid Methyl Ester

methanol

(2R,3S)-3-amino-2-hydroxy-5-methylhexanoic acid

Downstream raw materials:

(3S)-3-cyclohexylcarbonylamino-2-hydroxy-5-methylhexanoic acid methyl ester

(3S)-3-(N-t-butoxycarbonylamino)-2-hydroxy-5-methylhexanoic Acid Methyl Ester

Methyl (3S)-3-{N-[(+)-2-(1-naphthylmethyl)-3-(phenethylcarbamoyl)propionyl]-L-histidyl}amino-2-hydroxy-5-methylhexanoate

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