Technology Process of 2-(Dimethylamino)-6-methyl-4-pyridinecarboxylicacid
There total 6 articles about 2-(Dimethylamino)-6-methyl-4-pyridinecarboxylicacid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-chloro-6-methyl-isonicotinic acid tert.-butyl ester; dimethyl amine;
With
sodium t-butanolate;
palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene;
In
tetrahydrofuran;
at 110 ℃;
for 18h;
With
hydrogenchloride; water;
at 100 ℃;
for 18h;
With
sodium hydroxide;
In
water;
- Guidance literature:
-
2-chloro-6-methylisonicotinic acid ethyl ester; dimethyl amine;
With
sodium t-butanolate;
palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene;
In
tetrahydrofuran;
at 110 ℃;
for 42h;
Inert atmosphere;
With
hydrogenchloride;
In
water;
at 100 ℃;
for 18h;
With
sodium hydroxide;
In
water;
- Guidance literature:
-
C11H16N2O2;
With
hydrogenchloride; water;
at 100 ℃;
for 18h;
With
sodium hydroxide;
In
water;