(p-Chloro-Benzoyl)-phosphonic acid dimethyl ester

Base Information

Chemical Name:(p-Chloro-Benzoyl)-phosphonic acid dimethyl ester
CAS No.:33493-32-2
Molecular Formula:C9H10 Cl O4 P
Molecular Weight:248.603
Hs Code.:2931900090
DSSTox Substance ID:DTXSID80335802
Nikkaji Number:J452.655D
Wikidata:Q82102437
Mol file:33493-32-2.mol

Synonyms:33493-32-2;Dimethyl(4-chlorophenyloxomethyl)phosphonate;(p-Chloro-Benzoyl)-phosphonic acid dimethyl ester;(4-chlorophenyl)-dimethoxyphosphorylmethanone;dimethyl p-chlorobenzoylphosphonate;dimethyl 4-chlorobenzoylphosphonate;SCHEMBL4851005;DTXSID80335802;dimethyl (4-chlorobenzoyl)phosphonate;MFCD00800263;AKOS005067413;4-Chlorobenzoylphosphonic acid dimethyl ester;(4-Chloro-benzoyl)-phosphonic acid dimethyl ester

Suppliers and Price of (p-Chloro-Benzoyl)-phosphonic acid dimethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
DIMETHYL-(4-CHLOROPHENYLOXOMETHYL)PHOSPHONATE 95.00%
5G
$ 1468.65

Total 5 raw suppliers

Chemical Property of (p-Chloro-Benzoyl)-phosphonic acid dimethyl ester

Chemical Property:

PSA：62.41000
LogP:2.96610
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:248.0005235
Heavy Atom Count:15
Complexity:265

Purity/Quality:

99% ^*data from raw suppliers

DIMETHYL-(4-CHLOROPHENYLOXOMETHYL)PHOSPHONATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COP(=O)(C(=O)C1=CC=C(C=C1)Cl)OC

Technology Process of (p-Chloro-Benzoyl)-phosphonic acid dimethyl ester

There total 2 articles about (p-Chloro-Benzoyl)-phosphonic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 122-01-0
4-chloro-benzoyl chloride

: 121-45-9
phosphorous acid trimethyl ester

: 33493-32-2
dimethyl p-chlorobenzoylphosphonate

Guidance literature:: In toluene;

Reference yield:

: 33493-32-2
dimethyl p-chlorobenzoylphosphonate

Guidance literature:

Reference yield: 90.0%

: 75-52-5
nitromethane

: 33493-32-2
dimethyl p-chlorobenzoylphosphonate

: dimethyl [1-hydroxy-1-(4-chlorophenyl)-2-nitroethyl]phosphonate

Guidance literature:: nitromethane; With C₂₆H₃₄N₄O₂; In tert-butyl methyl ether; methoxybenzene; at 20 ℃; for 0.166667h;

dimethyl p-chlorobenzoylphosphonate; With 2,4-Dinitrophenol; In tert-butyl methyl ether; methoxybenzene; at -20 ℃; for 48h; optical yield given as %ee; enantioselective reaction;
DOI:10.1002/chem.200801958