1-(2,4-Dibromophenyl)ethanone

Base Information

• Chemical Name: 1-(2,4-Dibromophenyl)ethanone
• CAS No.: 33243-33-3
• Molecular Formula: C8H6Br2O
• Molecular Weight: 277.943
• Hs Code.: 2914700090
• DSSTox Substance ID: DTXSID50367877
• Nikkaji Number: J88.851F
• Wikidata: Q72463753
• Mol file: 33243-33-3.mol

Synonyms:1-(2,4-dibromophenyl)ethanone;33243-33-3;2',4'-DIBROMOACETOPHENONE;Ethanone, 1-(2,4-dibromophenyl)-;Ethanone,1-(2,4-dibromophenyl)-;1-(2,4-dibromophenyl)ethan-1-one;MFCD00152057;SCHEMBL1312703;Acetophenone, 2',4'-dibromo-;DTXSID50367877;AKOS001074165;AM61463;CS-W012302;BS-25229;SY034398;FT-0757245;EN300-01153;C15596;A875350;Z56886263;2 inverted exclamation mark ,4 inverted exclamation mark -Dibromoacetophenone

Chemical Property of 1-(2,4-Dibromophenyl)ethanone

Chemical Property:

• Melting Point: 61-62℃
• Boiling Point: 316.4 °C at 760 mmHg
• Flash Point: 117.6 °C
• PSA: 17.07000
• Density: 1.812 g/cm³
• LogP: 3.41420
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 277.87649
• Heavy Atom Count: 11
• Complexity: 158

Purity/Quality:

97% ^*data from raw suppliers

1-(2,4-Dibromophenyl)ethanone 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)C1=C(C=C(C=C1)Br)Br

Technology Process of 1-(2,4-Dibromophenyl)ethanone

There total 8 articles about 1-(2,4-Dibromophenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1,3-dibromobenzene (108-36-1) + acetyl chloride (75-36-5) → 2,4-dibromoacetophenone (33243-33-3)

Guidance literature:

With aluminum (III) chloride; at 100 ℃; for 1h; Inert atmosphere;

DOI:10.1002/adsc.201500953

Reference yield: 68.0%

1.4-dibromobenzene (106-37-6) + acetyl chloride (75-36-5) → 2,4-dibromoacetophenone (33243-33-3)

Guidance literature:

With aluminum (III) chloride; In dichloromethane; at -20 ℃; for 3h;

DOI:10.1016/j.cclet.2015.07.022

Reference yield:

1,3-dibromobenzene (108-36-1) + acetic anhydride (108-24-7) → 2,4-dibromoacetophenone (33243-33-3)

Guidance literature:

With aluminum (III) chloride; at 100 ℃; for 2h;

upstream raw materials:

1,3-dibromobenzene

acetyl chloride

carbon disulfide

aluminium trichloride

Downstream raw materials:

2,4-dibromobenzoic acid

2,4-Dibrom-phenacylidinchlorid

2-Diazo-3-(2,4-dibromo-phenyl)-3-oxo-propionaldehyde

2-(4-bromophenyl)-6-methoxyimidazo[1,2-a]pyridine