N-(-3-Acetylthiopropyl)phthalimide

Base Information

• Chemical Name: N-(-3-Acetylthiopropyl)phthalimide
• CAS No.: 221218-66-2
• Molecular Formula: C₁₃H₁₃NO₃S
• Molecular Weight: 263.317
• DSSTox Substance ID: DTXSID40408586
• Nikkaji Number: J1.033.180C
• Mol file: 221218-66-2.mol

Synonyms:N-(-3-Acetylthiopropyl)phthalimide;221218-66-2;S-[3-(1,3-dioxoisoindol-2-yl)propyl] ethanethioate;S-(3-(1,3-dioxoisoindolin-2-yl)propyl) ethanethioate;SCHEMBL9970727;DTXSID40408586;N-(3-Acetylthiopropyl)phthalimide;QDCSBRSBDZXURK-UHFFFAOYSA-N;MFCD00189168;AKOS024319401;N-(3-Acetylthiopropyl)phthalimide 97;N-(-3-Acetylthiopropyl)phthalimide, 97%;J-014525;S-3-(1,3-dioxoisoindolin-2-yl)propyl ethanethioate;S-[3-(1, 3-dioxoisoindol-2-yl)propyl] ethanethioate;2-[3-(acetylsulfanyl)propyl]-2,3-dihydro-1H-isoindole-1,3-dione;THIOACETIC ACID 3-(1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-PROPYL ESTER

Chemical Property of N-(-3-Acetylthiopropyl)phthalimide

Chemical Property:

• Vapor Pressure: 8.36E-07mmHg at 25°C
• Melting Point: 90-94 °C(lit.)
• Refractive Index: 1.602
• Boiling Point: 406.1ºC at 760 mmHg
• Flash Point: 199.4ºC
• PSA: 79.75000
• Density: 1.311g/cm3
• LogP: 1.89030
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 263.06161445
• Heavy Atom Count: 18
• Complexity: 345

Purity/Quality:

99%, ^*data from raw suppliers

N-(-3-Acetylthiopropyl)phthalimide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(=O)SCCCN1C(=O)C2=CC=CC=C2C1=O

Technology Process of N-(-3-Acetylthiopropyl)phthalimide

There total 5 articles about N-(-3-Acetylthiopropyl)phthalimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-(3-bromopropyl)isoindole-1,3-dione (5460-29-7) + potassium thioacetate (10387-40-3) → S-[3-(1,3-dioxoisoindolin-2-yl)propyl] ethanethioate (221218-66-2)

Guidance literature:

In tetrahydrofuran; for 24h; Reflux;

DOI:10.1039/c9ta04018h

Reference yield: 91.0%

3-phthalimido-1-propene (5428-09-1) + tiolacetic acid (507-09-5) → S-[3-(1,3-dioxoisoindolin-2-yl)propyl] ethanethioate (221218-66-2)

Guidance literature:

With benzo[de]benzo[4,5]imidazo[2,1-a]isoquinolin-7-one; In ethyl acetate; at 20 ℃; for 1h; Inert atmosphere; Sealed tube; Irradiation;

DOI:10.1021/acs.joc.9b01331

Reference yield: 86.0%

N-(3-chloropropyl)phthalimide (42251-84-3) + potassium thioacetate (10387-40-3) → S-[3-(1,3-dioxoisoindolin-2-yl)propyl] ethanethioate (221218-66-2)

Guidance literature:

In tetrahydrofuran; at 85 ℃; for 4h;

DOI:10.1039/c8cc04467h

upstream raw materials:

2-(3-bromopropyl)isoindole-1,3-dione

potassium thioacetate

potassium phtalimide

phthalic anhydride

Downstream raw materials:

2-<3-(Benzylthio)propyl>-1H-isoindole-1,3(2H)-dione

2-(3-mercaptopropyl)isoindoline-1,3-dione

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 221218-66-2 N-(3-ACETYLTHIOPROPYL)PHTHALIMIDE 97

Send

Send

Metric Ton KG G Pound L ML

Send

Send