3-(Chloromethyl)-1,1,2,2-tetrafluorocyclobutane

Base Information

• Chemical Name: 3-(Chloromethyl)-1,1,2,2-tetrafluorocyclobutane
• CAS No.: 356-80-9
• Molecular Formula: C5H5 Cl F4
• Molecular Weight: 176.54
• Hs Code.: 2903890090
• DSSTox Substance ID: DTXSID60382011
• Mol file: 356-80-9.mol

Synonyms:356-80-9;1-Chloromethyl-2,2,3,3-tetrafluorocyclobutane;3-(chloromethyl)-1,1,2,2-tetrafluorocyclobutane;SCHEMBL7355095;DTXSID60382011;FT-0607649;A822938;3-(chloromethyl)-1,1,2,2-tetrakis(fluoranyl)cyclobutane

Chemical Property of 3-(Chloromethyl)-1,1,2,2-tetrafluorocyclobutane

Chemical Property:

• Vapor Pressure: 18.9mmHg at 25°C
• Refractive Index: 1.373
• Boiling Point: 119.6°Cat760mmHg
• Flash Point: 25.8°C
• PSA: 0.00000
• Density: 1.39g/cm³
• LogP: 2.51570
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 176.0015905
• Heavy Atom Count: 10
• Complexity: 145

Purity/Quality:

99% ^*data from raw suppliers

1-CHLOROMETHYL-2,2,3,3-TETRAFLUOROCYCLOBUTANE 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(C(C1(F)F)(F)F)CCl

Technology Process of 3-(Chloromethyl)-1,1,2,2-tetrafluorocyclobutane

There total 1 articles about 3-(Chloromethyl)-1,1,2,2-tetrafluorocyclobutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

polytetrafluoroethylene (116-14-3,82785-14-6) + 3-chloroprop-1-ene (107-05-1) → 3-chloromethyl-1,1,2,2-tetrafluoro-cyclobutane (356-80-9)

Guidance literature:

at 380 - 400 ℃; for 0.00833333h;

Reference yield:

3-hydroxy-4-methoxybenzoate (6702-50-7) + 3-chloromethyl-1,1,2,2-tetrafluoro-cyclobutane (356-80-9) → methyl 3-(4,4-difluoro-3-methylenecyclobut-1-enyloxy)-4-methoxybenzoate

Guidance literature:

With potassium iodide; potassium carbonate; In N,N-dimethyl-formamide;

upstream raw materials:

polytetrafluoroethylene

3-chloroprop-1-ene

Refernces