[2-chloro-6-fluoro-4-(4-fluoro-benzoyl)-phenoxy]acetic acid hydrazide

Base Information

• Chemical Name: [2-chloro-6-fluoro-4-(4-fluoro-benzoyl)-phenoxy]acetic acid hydrazide
• CAS No.: 1443038-07-0
• Molecular Formula: C₁₅H₁₁ClF₂N₂O₃
• Molecular Weight: 340.714
• Mol file: 1443038-07-0.mol

Synonyms:[2-chloro-6-fluoro-4-(4-fluoro-benzoyl)-phenoxy]acetic acid hydrazide

Chemical Property of [2-chloro-6-fluoro-4-(4-fluoro-benzoyl)-phenoxy]acetic acid hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2-chloro-6-fluoro-4-(4-fluoro-benzoyl)-phenoxy]acetic acid hydrazide

There total 7 articles about [2-chloro-6-fluoro-4-(4-fluoro-benzoyl)-phenoxy]acetic acid hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

[4-(4-fluorobenzoyl)-2-chloro-6-fluorophenoxy]ethanoic acid (1443038-02-5) → [2-chloro-6-fluoro-4-(4-fluoro-benzoyl)-phenoxy]acetic acid hydrazide (1443038-07-0)

Guidance literature:

With hydrazine hydrate; In ethanol; at 0 ℃; for 1h;

DOI:10.1016/j.ejmech.2013.02.040

Reference yield: 79.0%

(4-fluorobenzoyl-2-chloro-6-fluorophenoxy)acetic acid ethyl ester → [2-chloro-6-fluoro-4-(4-fluoro-benzoyl)-phenoxy]acetic acid hydrazide (1443038-07-0)

Guidance literature:

With hydrazine hydrate; In ethanol; at 20 ℃; for 3h;

DOI:10.1039/c7md00593h

Reference yield: 76.0%

ethyl [2-(4-fluorobenzoyl)-2-chloro-6-fluorophenoxy]acetate (1443037-97-5) → [2-chloro-6-fluoro-4-(4-fluoro-benzoyl)-phenoxy]acetic acid hydrazide (1443038-07-0)

Guidance literature:

With hydrazine hydrate; In ethanol; at 20 ℃; for 2h;

DOI:10.1016/j.bioorg.2016.02.001

upstream raw materials:

2-chloro-6-fluorophenyl-4-fluorobenzoate

(3-chloro-5-fluoro-4-hydroxyphenyl)-4-fluorophenyl methanone

ethyl [2-(4-fluorobenzoyl)-2-chloro-6-fluorophenoxy]acetate

[4-(4-fluorobenzoyl)-2-chloro-6-fluorophenoxy]ethanoic acid

Downstream raw materials:

N,N-di[di(2-chloro-6-fluoro-4-(4-fluoro-benzoyl)phenoxy)]acetyl hydrazide

2,5-di[2-fluoro-4-(4-fluoro)benzoyl-6-chlorophenoxymethyl]-1,3,4-oxadiazole