N,N'-bis[6-(2-ethylhexanoylamino)pyrid-2-yl]-5-nitroisophthalamide

Base Information

• Chemical Name: N,N'-bis[6-(2-ethylhexanoylamino)pyrid-2-yl]-5-nitroisophthalamide
• CAS No.: 1299474-88-6
• Molecular Formula: C₃₄H₄₃N₇O₆
• Molecular Weight: 645.759
• Mol file: 1299474-88-6.mol

Synonyms:N,N'-bis[6-(2-ethylhexanoylamino)pyrid-2-yl]-5-nitroisophthalamide

Chemical Property of N,N'-bis[6-(2-ethylhexanoylamino)pyrid-2-yl]-5-nitroisophthalamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-bis[6-(2-ethylhexanoylamino)pyrid-2-yl]-5-nitroisophthalamide

There total 3 articles about N,N'-bis[6-(2-ethylhexanoylamino)pyrid-2-yl]-5-nitroisophthalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

1,3-bis<<(6-aminopyrid-2-yl)amino>carbonyl>-5-nitrobenzene (129648-68-6) + 2-ethylhexanoic acid chloride (760-67-8) → N,N'-bis[6-(2-ethylhexanoylamino)pyrid-2-yl]-5-nitroisophthalamide (1299474-88-6)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1002/ejoc.201001684

Reference yield:

5-nitro-1,3-benzenedicarbonylchloride (13438-30-7) → N,N'-bis[6-(2-ethylhexanoylamino)pyrid-2-yl]-5-nitroisophthalamide (1299474-88-6)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 3 h / 20 °C

2: triethylamine / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere

With triethylamine; In tetrahydrofuran;

DOI:10.1002/ejoc.201001684

Reference yield:

5-nitrobenzene-1,3-dicarboxylic acid (618-88-2) → N,N'-bis[6-(2-ethylhexanoylamino)pyrid-2-yl]-5-nitroisophthalamide (1299474-88-6)

Guidance literature:

Multi-step reaction with 3 steps

1: oxalyl dichloride / toluene

2: triethylamine / tetrahydrofuran / 3 h / 20 °C

3: triethylamine / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere

With oxalyl dichloride; triethylamine; In tetrahydrofuran; toluene;

DOI:10.1002/ejoc.201001684

upstream raw materials:

5-nitro-1,3-benzenedicarbonylchloride

5-nitrobenzene-1,3-dicarboxylic acid

1,3-bis<<(6-aminopyrid-2-yl)amino>carbonyl>-5-nitrobenzene

2-ethylhexanoic acid chloride