Trans-N-benzyloxycarbonyl-N-methyl cyclobutanamine-3-acetaldehyde Diethyl Acetal

Base Information

Chemical Name:Trans-N-benzyloxycarbonyl-N-methyl cyclobutanamine-3-acetaldehyde Diethyl Acetal
CAS No.:171550-00-8
Molecular Formula:C₁₉H₂₉NO₄
Molecular Weight:335.444
Hs Code.:

Synonyms:Trans-N-benzyloxycarbonyl-N-methyl cyclobutanamine-3-acetaldehyde Diethyl Acetal

Suppliers and Price of Trans-N-benzyloxycarbonyl-N-methyl cyclobutanamine-3-acetaldehyde Diethyl Acetal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Trans-N-benzyloxycarbonyl-N-methyl cyclobutanamine-3-acetaldehyde Diethyl Acetal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Trans-N-benzyloxycarbonyl-N-methyl cyclobutanamine-3-acetaldehyde Diethyl Acetal

There total 5 articles about Trans-N-benzyloxycarbonyl-N-methyl cyclobutanamine-3-acetaldehyde Diethyl Acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 4-[3-(trans-3-methylaminocyclobutyl)-1H-indol-5-ylmethyl]-(4S)oxazolidin-2-one

: 171550-00-8
Trans-N-benzyloxycarbonyl-N-methyl cyclobutanamine-3-acetaldehyde Diethyl Acetal

Guidance literature:

Reference yield:

: 171549-99-8
trans-N-(benzyloxycarbonyl)cyclobutanamine-3-acetaldehyde diethyl acetal

: 74-88-4
methyl iodide

: 171550-00-8
Trans-N-benzyloxycarbonyl-N-methyl cyclobutanamine-3-acetaldehyde Diethyl Acetal

Guidance literature:: trans-N-(benzyloxycarbonyl)cyclobutanamine-3-acetaldehyde diethyl acetal; With sodium hydride; In N,N-dimethyl-formamide; at 10 ℃; for 0.5h;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃; for 2h; Further stages.;
DOI:10.1021/jm000956k

Reference yield:

: 1-Isocyanato-3-methylene-cyclobutane

: 171550-00-8
Trans-N-benzyloxycarbonyl-N-methyl cyclobutanamine-3-acetaldehyde Diethyl Acetal

Guidance literature:: Multi-step reaction with 4 steps

1.1: DPPA

2.1: 19.5 percent / H₂; (Ph₃P)3RhCl / toluene / 18 h / 70 °C / 76000 Torr

3.1: 94 percent / pTsOH / ethanol / 3 h / Heating

4.1: NaH / dimethylformamide / 0.5 h / 10 °C

4.2: dimethylformamide / 2 h / 20 °C

With Wilkinson's catalyst; diphenyl-phosphinic acid; hydrogen; sodium hydride; toluene-4-sulfonic acid; In ethanol; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm000956k