Chemical Property of Dalcetrapib
Chemical Property:
- Melting Point:63-63.5 °C
- Boiling Point:528.912 °C at 760 mmHg
- PKA:13.95±0.70(Predicted)
- Flash Point:273.676 °C
- PSA：71.47000
- Density:1.066 g/cm3
- LogP:6.74960
- Storage Temp.:Sealed in dry,Store in freezer, under -20°C
- Solubility.:insoluble in H2O; ≥12.7 mg/mL in DMSO; ≥80.2 mg/mL in EtOH
- XLogP3:7.1
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:9
- Exact Mass:389.23885053
- Heavy Atom Count:27
- Complexity:481
- Purity/Quality:
-
99%, *data from raw suppliers
Dalcetrapib *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CCC(CC)CC1(CCCCC1)C(=O)NC2=CC=CC=C2SC(=O)C(C)C
- Recent ClinicalTrials:Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS
- Recent EU Clinical Trials:A phase III, double-blind, randomized placebo-controlled study to evaluate the effects of dalcetrapib on cardiovascular (CV) risk in a genetically defined population with a recent Acute Coronary Syndrome (ACS): The dal-GenE trial
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Uses
Dalcetrapib is a cholesteryl ester transfer protein (CETP) inhibitor. Dalcetrapib is a drug undergoing trials for the treatment of cardiovascular disease, dyslipidemia, peripheral arterial disease (PA
D). Dalcetrapib is a cholesteryl ester transfer protein (CETP) inhibitor. Dalcetrapib is a drug undergoing trials for the treatment of cardiovascular disease, dyslipidemia, peripheral arterial disease (PAD).
