CETP inhibitors

CETP inhibitors are compounds that inhibit the activity of cholesteryl ester transfer protein (CETP), a plasma protein that facilitates the transfer of cholesteryl esters and triglycerides between lipoproteins. By blocking CETP, these inhibitors aim to increase high-density lipoprotein (HDL) cholesterol levels and decrease low-density lipoprotein (LDL) cholesterol levels, potentially reducing the risk of cardiovascular diseases. CETP inhibitors have been investigated for their potential to improve lipid profiles and provide cardiovascular benefits. However, their development has faced challenges, including concerns about efficacy and safety.