Technology Process of (3,4-dibromophenyl)phenylmethanol
There total 4 articles about (3,4-dibromophenyl)phenylmethanol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1,2-dibromo-4-iodobenzene;
With
isopropylmagnesium chloride;
In
tetrahydrofuran;
at -78 ℃;
for 3h;
Inert atmosphere;
benzaldehyde;
In
tetrahydrofuran;
at -78 - 25 ℃;
Inert atmosphere;
DOI:10.1002/ejoc.201001217
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium iodide / water; acetone / 0.5 h / 25 °C
2.1: isopropylmagnesium chloride / tetrahydrofuran / 3 h / -78 °C / Inert atmosphere
2.2: -78 - 25 °C / Inert atmosphere
With
isopropylmagnesium chloride; potassium iodide;
In
tetrahydrofuran; water; acetone;
1.1: Sandmeyer iodination;
DOI:10.1002/ejoc.201001217
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: tetrafluoroboric acid; sodium nitrite / water / 0.5 h / 0 °C
2.1: potassium iodide / water; acetone / 0.5 h / 25 °C
3.1: isopropylmagnesium chloride / tetrahydrofuran / 3 h / -78 °C / Inert atmosphere
3.2: -78 - 25 °C / Inert atmosphere
With
tetrafluoroboric acid; isopropylmagnesium chloride; potassium iodide; sodium nitrite;
In
tetrahydrofuran; water; acetone;
2.1: Sandmeyer iodination;
DOI:10.1002/ejoc.201001217
