7,4'-DIMETHOXYFLAVONE

Base Information

• Chemical Name: 7,4'-DIMETHOXYFLAVONE
• CAS No.: 20979-50-4
• Molecular Formula: C17H14O4
• Molecular Weight: 282.296
• Hs Code.: 2914509090
• Mol file: 20979-50-4.mol

Synonyms:Flavone,4',7-dimethoxy- (7CI,8CI);4',7-Dimethoxyflavone;7-Methoxy-2-(4-methoxyphenyl)chromone;

Chemical Property of 7,4'-DIMETHOXYFLAVONE

Chemical Property:

• Vapor Pressure: 2.18E-08mmHg at 25°C
• Melting Point: 143-144 °C
• Refractive Index: 1.598
• Boiling Point: 452.764 °C at 760 mmHg
• Flash Point: 202.222 °C
• PSA: 48.67000
• Density: 1.242 g/cm³
• LogP: 3.47720

Purity/Quality:

98%,99%, ^*data from raw suppliers

7,4''-Dimethoxyflavone ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Flavonoids for promoting wound healing and preventing skin aging.

Technology Process of 7,4'-DIMETHOXYFLAVONE

There total 47 articles about 7,4'-DIMETHOXYFLAVONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

pratol (487-24-1) + methyl iodide (74-88-4) → 4,7-dimethoxyflavone (20979-50-4)

Guidance literature:

With potassium carbonate;

DOI:10.1016/j.bmc.2016.03.064

Reference yield: 82.0%

2'-hydroxy-4,4'-dimethoxychalcone (2198-19-8,62881-44-1) → 4,7-dimethoxyflavone (20979-50-4)

Guidance literature:

With tert.-butylhydroperoxide; sodium tetrachloropalladate(II) trihydrate; sodium acetate; In water; acetic acid; tert-butyl alcohol; at 70 ℃; for 2.5h;

DOI:10.1016/j.tetlet.2009.12.107

Reference yield: 81.0%

1-(2-hydroxy-4-methoxyphenyl)ethanone (552-41-0) + 4-methoxy-benzaldehyde (123-11-5) → 4,7-dimethoxyflavone (20979-50-4)

Guidance literature:

With pyrrolidine; iodine; In dimethyl sulfoxide; at 150 ℃; for 8h;

DOI:10.1016/j.tetlet.2014.04.051

upstream raw materials:

1-(2-hydroxy-4-methoxyphenyl)-3-(4-methoxyphenyl)-propan-1-one

2-(4-hydroxyphenyl)-7-methoxychromen-4-one

dimethyl sulfate

4',7-dimethoxyflavanone

Downstream raw materials:

2-amino-5-(4-methoxyphenyl)-6-(2-hydroxy-4-methoxyphenyl)pyrimidine

7,4'-Dihydroxyflavon

pratol

C₁₇H₁₄O₃S

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