2-Diethylamino-5-nitropyridine

Base Information

• Chemical Name: 2-Diethylamino-5-nitropyridine
• CAS No.: 20168-70-1
• Molecular Formula: C₉H₁₃N₃O₂
• Molecular Weight: 195.221
• Hs Code.: 2933399990
• Mol file: 20168-70-1.mol

Synonyms:u202fN,N-diethyl-5-nitropyridin-2-amine

Chemical Property of 2-Diethylamino-5-nitropyridine

Chemical Property:

• Melting Point: 167 °C
• Boiling Point: 323.3±27.0 °C(Predicted)
• PKA: 3.58±0.10(Predicted)
• Density: 1.179±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

N,N-Diethyl-5-nitropyridin-2-amine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Diethylamino-5-nitropyridine

There total 15 articles about 2-Diethylamino-5-nitropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-Fluoro-5-nitropyridine (456-24-6) + triethylamine (121-44-8) → u202fN,N-diethyl-5-nitropyridin-2-amine (20168-70-1)

Guidance literature:

With tris[2-phenylpyridinato-C₂,N]iridium(III); In dimethyl sulfoxide; at 20 ℃; for 15h; Irradiation;

DOI:10.3390/molecules26113323

Reference yield: 98.0%

2-chloro-5-nitropyridine (4548-45-2) + diethylamine (109-89-7) → u202fN,N-diethyl-5-nitropyridin-2-amine (20168-70-1)

Guidance literature:

In ethanol; at 30 ℃; for 4h;

DOI:10.1021/ja405637b

Reference yield: 82.0%

2-chloro-5-nitropyridine (4548-45-2) + triethylamine (121-44-8) → u202fN,N-diethyl-5-nitropyridin-2-amine (20168-70-1)

Guidance literature:

at 100 ℃; for 96h; under 6000480 Torr;

DOI:10.1039/c39910000306

upstream raw materials:

2-chloro-5-nitropyridine

triethylamine

N-ethyl-N-hydroxy-ethanamine

2-bromo-5-nitropyridine

Downstream raw materials:

2-diethylamino-5-amino pyridine