3-Amino-5-(trifluoromethyl)benzamide

Base Information

Chemical Name:3-Amino-5-(trifluoromethyl)benzamide
CAS No.:20566-95-4
Molecular Formula:C8H7 F3 N2 O
Molecular Weight:204.15
Hs Code.:2924299090
DSSTox Substance ID:DTXSID20440727
Wikidata:Q82257105
Mol file:20566-95-4.mol

Synonyms:3-amino-5-(trifluoromethyl)benzamide;20566-95-4;3-amino-5-trifluoromethyl-benzamide;Benzamide, 3-amino-5-(trifluoromethyl)-;SCHEMBL4472344;DTXSID20440727;MFCD06637329;AKOS005259365;FT-0692061;EN300-8662652

Suppliers and Price of 3-Amino-5-(trifluoromethyl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-AMINO-5-(TRIFLUOROMETHYL)BENZAMIDE 95.00%
5G
$ 2411.75

American Custom Chemicals Corporation
3-AMINO-5-(TRIFLUOROMETHYL)BENZAMIDE 95.00%
1G
$ 1092.27

Total 6 raw suppliers

Chemical Property of 3-Amino-5-(trifluoromethyl)benzamide

Chemical Property:

Vapor Pressure:0.004mmHg at 25°C
Refractive Index:1.529
Boiling Point:277.883°C at 760 mmHg
Flash Point:121.86°C
PSA：69.11000
Density:1.418g/cm³
LogP:2.66800
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:204.05104734
Heavy Atom Count:14
Complexity:229

Purity/Quality:

99% ^*data from raw suppliers

3-AMINO-5-(TRIFLUOROMETHYL)BENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C=C1C(F)(F)F)N)C(=O)N

Technology Process of 3-Amino-5-(trifluoromethyl)benzamide

There total 4 articles about 3-Amino-5-(trifluoromethyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1336-21-6
ammonium hydroxide

: 79-37-8
oxalyl dichloride

: 328-80-3
3-nitro-5-trifluoromethyl-benzoic acid

: 20566-95-4
3-carboxamide-5-trifluoromethylaniline

Guidance literature:: palladium-carbon; In tetrahydrofuran; ethanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 20566-89-6
3-nitro-5-(trifluoromethyl)benzamide

: 20566-95-4
3-carboxamide-5-trifluoromethylaniline

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; for 18h;
DOI:10.1021/jm970671g

Reference yield:

: 782-79-6
3-nitro-5-trifluoromethyl-benzoyl chloride

: 20566-95-4
3-carboxamide-5-trifluoromethylaniline

Guidance literature:: Multi-step reaction with 2 steps

1: NH₄OH / tetrahydrofuran / 18 h

2: H₂ / 5percent Pd/C / ethanol / 18 h

With ammonium hydroxide; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethanol;
DOI:10.1021/jm970671g