5-Methoxyacetamido-2,4,6-triiodoisophthaloyl chloride

Base Information

• Chemical Name: 5-Methoxyacetamido-2,4,6-triiodoisophthaloyl chloride
• CAS No.: 76350-03-3
• Molecular Formula: C₁₁H₆Cl₂I₃NO₄
• Molecular Weight: 667.792
• Mol file: 76350-03-3.mol

Synonyms:5-Methoxyacetamido-2,4,6-triiodoisophthaloyl chloride

Chemical Property of 5-Methoxyacetamido-2,4,6-triiodoisophthaloyl chloride

Chemical Property:

• Boiling Point: 628.2±55.0 °C(Predicted)
• PKA: 10.32±0.70(Predicted)
• Density: 2.525±0.06 g/cm3(Predicted)

Purity/Quality:

99.0% Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-Methoxyacetamido-2,4,6-triiodoisophthaloyl chloride

There total 2 articles about 5-Methoxyacetamido-2,4,6-triiodoisophthaloyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

Methoxyacetyl chloride (38870-89-2) + 5-amino-2,4,6-triiodoisophthalic acid dichloride (37441-29-5) → 5-Methoxyacetamido-2,4,6-triiodoisophthaloyl chloride (76350-03-3)

Guidance literature:

In 1,4-dioxane; at 80 - 90 ℃;

Reference yield: 90.0%

2-methoxyacetic acid (625-45-6) + 5-amino-2,4,6-triiodoisophthalic acid dichloride (37441-29-5) → 5-Methoxyacetamido-2,4,6-triiodoisophthaloyl chloride (76350-03-3)

Guidance literature:

2-methoxyacetic acid; With bis(trichloromethyl) carbonate; In dichloromethane; for 3h; Reflux;

5-amino-2,4,6-triiodoisophthalic acid dichloride; In dichloromethane; N,N-dimethyl acetamide; water; for 5.5h;

Reference yield: 95.0%

5-Methoxyacetamido-2,4,6-triiodoisophthaloyl chloride (76350-03-3) + 3-Amino-1,2-propanediol (616-30-8,13552-31-3,98923-21-8) → 5-methoxyacetylamino-2,4,6-triiodoisophthalic acid (2,3-dihydroxypropyl)amide chloride (76350-04-4)

Guidance literature:

With dmap; at 30 ℃; for 10h; Temperature;

upstream raw materials:

Methoxyacetyl chloride

5-amino-2,4,6-triiodoisophthalic acid dichloride

2-methoxyacetic acid

Downstream raw materials:

5-methoxyacetylamino-2,4,6-triiodoisophthalic acid (2,3-dihydroxypropyl)amide chloride

iopromide