[1-(2-benzyloxy-ethyl)-but-3-enyloxy]-chloro-diisopropyl-silane

Base Information

• Chemical Name: [1-(2-benzyloxy-ethyl)-but-3-enyloxy]-chloro-diisopropyl-silane
• CAS No.: 863638-78-2
• Molecular Formula: C₁₉H₃₁ClO₂Si
• Molecular Weight: 354.992
• Mol file: 863638-78-2.mol

Synonyms:[1-(2-benzyloxy-ethyl)-but-3-enyloxy]-chloro-diisopropyl-silane

Chemical Property of [1-(2-benzyloxy-ethyl)-but-3-enyloxy]-chloro-diisopropyl-silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [1-(2-benzyloxy-ethyl)-but-3-enyloxy]-chloro-diisopropyl-silane

There total 1 articles about [1-(2-benzyloxy-ethyl)-but-3-enyloxy]-chloro-diisopropyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Diisopropylsilyl dichloride (7751-38-4) + (R)-1-benzyloxy-hex-5-en-3-ol (111322-01-1,119239-98-4,91285-62-0) → [1-(2-benzyloxy-ethyl)-but-3-enyloxy]-chloro-diisopropyl-silane (863638-78-2)

Guidance literature:

With 1H-imidazole; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1039/b505746a

Reference yield:

[1-(2-benzyloxy-ethyl)-but-3-enyloxy]-chloro-diisopropyl-silane (863638-78-2) → (3S)-5-benzyloxy-3-(benzyloxy-diisopropyl-silanyloxy)-pentanal (863638-83-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 6.08 g / CH₂Cl₂ / 20 °C

2: 77 percent / aq. OsO₄; NMO / acetone; 2-methyl-propan-2-ol / 48 h / 20 °C

3: 65 percent / Na₂CO₃; Pb(OAc)4 / CH₂Cl₂ / 0.33 h / 0 °C

With lead(IV) acetate; osmium(VIII) oxide; N-methyl-2-indolinone; sodium carbonate; In dichloromethane; acetone; tert-butyl alcohol;

DOI:10.1039/b505746a

Reference yield:

[1-(2-benzyloxy-ethyl)-but-3-enyloxy]-chloro-diisopropyl-silane (863638-78-2) → (2RS,4S)-6-benzyloxy-4-(benzyloxy-diisopropyl-silanyloxy)-hexane-1,2-diol

Guidance literature:

Multi-step reaction with 2 steps

1: 6.08 g / CH₂Cl₂ / 20 °C

2: 77 percent / aq. OsO₄; NMO / acetone; 2-methyl-propan-2-ol / 48 h / 20 °C

With osmium(VIII) oxide; N-methyl-2-indolinone; In dichloromethane; acetone; tert-butyl alcohol;

DOI:10.1039/b505746a

upstream raw materials:

Diisopropylsilyl dichloride

(R)-1-benzyloxy-hex-5-en-3-ol

Downstream raw materials:

(1R)-benzyloxy-[1-(2-benzyloxy-ethyl)-but-3-enyloxy]-diisopropyl-silane

(3S)-5-benzyloxy-3-(benzyloxy-diisopropyl-silanyloxy)-pentanal

(4S,6S)-8-benzyloxy-6-(benzyloxy-diisopropyl-silanyloxy)-4-hydroxy-octan-2-one

(4S,6S)-8-benzyloxy-6-(benzyloxy-diisopropyl-silanyloxy)-4-(tert-butyldimethyl-silanyloxy)-octan-2-one