3-[(2S)-2-benzyloxy-4-(4-methoxyphenoxy)-2-methylbutyl]-2-(dimethyl-{2-[2,3,5,6-tetrabromo-4-(tert-butyldimethylsilanyloxy)phenoxy]ethyl}silanyl)furan

Base Information

Chemical Name:3-[(2S)-2-benzyloxy-4-(4-methoxyphenoxy)-2-methylbutyl]-2-(dimethyl-{2-[2,3,5,6-tetrabromo-4-(tert-butyldimethylsilanyloxy)phenoxy]ethyl}silanyl)furan
CAS No.:915769-90-3
Molecular Formula:C₃₉H₅₀Br₄O₆Si₂
Molecular Weight:990.609
Hs Code.:

3-[(2S)-2-benzyloxy-4-(4-methoxyphenoxy)-2-methylbutyl]-2-(dimethyl-{2-[2,3,5,6-tetrabromo-4-(tert-butyldimethylsilanyloxy)phenoxy]ethyl}silanyl)furan

Synonyms:3-[(2S)-2-benzyloxy-4-(4-methoxyphenoxy)-2-methylbutyl]-2-(dimethyl-{2-[2,3,5,6-tetrabromo-4-(tert-butyldimethylsilanyloxy)phenoxy]ethyl}silanyl)furan

Suppliers and Price of 3-[(2S)-2-benzyloxy-4-(4-methoxyphenoxy)-2-methylbutyl]-2-(dimethyl-{2-[2,3,5,6-tetrabromo-4-(tert-butyldimethylsilanyloxy)phenoxy]ethyl}silanyl)furan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-[(2S)-2-benzyloxy-4-(4-methoxyphenoxy)-2-methylbutyl]-2-(dimethyl-{2-[2,3,5,6-tetrabromo-4-(tert-butyldimethylsilanyloxy)phenoxy]ethyl}silanyl)furan

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-[(2S)-2-benzyloxy-4-(4-methoxyphenoxy)-2-methylbutyl]-2-(dimethyl-{2-[2,3,5,6-tetrabromo-4-(tert-butyldimethylsilanyloxy)phenoxy]ethyl}silanyl)furan

There total 14 articles about 3-[(2S)-2-benzyloxy-4-(4-methoxyphenoxy)-2-methylbutyl]-2-(dimethyl-{2-[2,3,5,6-tetrabromo-4-(tert-butyldimethylsilanyloxy)phenoxy]ethyl}silanyl)furan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 915769-89-0
2,3,5,6-tetrabromo-4-(tert-butyldimethylsilanyloxy)-1-phenol

: 915769-83-4
(2S)-2-({3-[2-benzyloxy-4-(4-methoxyphenoxy)-2-methylbutyl]furan-2-yl}dimethylsilanyl)ethanol

: 915769-90-3
3-[(2S)-2-benzyloxy-4-(4-methoxyphenoxy)-2-methylbutyl]-2-(dimethyl-{2-[2,3,5,6-tetrabromo-4-(tert-butyldimethylsilanyloxy)phenoxy]ethyl}silanyl)furan

Guidance literature:: With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; for 3h;
DOI:10.1021/ja0652619

Reference yield:

: 169310-73-0
1-methoxy-4-((3-methylbut-3-en-1-yl)oxy)benzene

: 915769-90-3
3-[(2S)-2-benzyloxy-4-(4-methoxyphenoxy)-2-methylbutyl]-2-(dimethyl-{2-[2,3,5,6-tetrabromo-4-(tert-butyldimethylsilanyloxy)phenoxy]ethyl}silanyl)furan

Guidance literature:: Multi-step reaction with 8 steps

1.1: 95 percent / K₂OsO₂(OH)4; K₂CO₃; DHQ₂PHAL / K₃Fe(CN)6 / 2-methyl-propan-2-ol; H₂O / 24 h / 0 °C

2.1: 90 percent / triethylamine; 4-(dimethylamino)pyridine / CH₂Cl₂ / 48 h / 20 °C

3.1: n-BuLi / tetrahydrofuran; hexane / -78 °C

3.2: 84 percent / BF₃*Et₂O / tetrahydrofuran; hexane / 1 h / -78 °C

4.1: 100 percent / KH / dimethylformamide / 0.75 h / 0 °C

5.1: 86 percent / N-bromosuccinimide / dimethylformamide / 1 h / 0 °C

6.1: n-BuLi / tetrahydrofuran / 0.42 h / -78 °C

6.2: 88 percent / tetrahydrofuran / 0.42 h / -78 °C

7.1: 9-BBN / tetrahydrofuran / 3 h / 20 °C

7.2: 96 percent / aq. NaOH; aq. H₂O₂ / tetrahydrofuran / 0.5 h / 0 °C

8.1: 75 percent / diisopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 3 h / 20 °C

With dmap; N-Bromosuccinimide; 9-borabicyclo[3.3.1]nonane dimer; n-butyllithium; potassium dioxotetrahydroxoosmate(VI); di-isopropyl azodicarboxylate; potassium hydride; potassium carbonate; hydroquinidein 1,4-phthalazinediyl diether; triethylamine; triphenylphosphine; potassium hexacyanoferrate(III); In tetrahydrofuran; hexane; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol; 1.1: Sharpless asymmetric dihydroxylation / 8.1: Mitsunobu coupling;
DOI:10.1016/j.tet.2007.04.031

Reference yield:

: 209118-78-5
(2S)-4-(4-methoxyphenoxy)-2-methylbutane-1,2-diol

: 915769-90-3
3-[(2S)-2-benzyloxy-4-(4-methoxyphenoxy)-2-methylbutyl]-2-(dimethyl-{2-[2,3,5,6-tetrabromo-4-(tert-butyldimethylsilanyloxy)phenoxy]ethyl}silanyl)furan

Guidance literature:: Multi-step reaction with 7 steps

1.1: 90 percent / triethylamine; 4-(dimethylamino)pyridine / CH₂Cl₂ / 48 h / 20 °C

2.1: n-BuLi / tetrahydrofuran; hexane / -78 °C

2.2: 84 percent / BF₃*Et₂O / tetrahydrofuran; hexane / 1 h / -78 °C

3.1: 100 percent / KH / dimethylformamide / 0.75 h / 0 °C

4.1: 86 percent / N-bromosuccinimide / dimethylformamide / 1 h / 0 °C

5.1: n-BuLi / tetrahydrofuran / 0.42 h / -78 °C

5.2: 88 percent / tetrahydrofuran / 0.42 h / -78 °C

6.1: 9-BBN / tetrahydrofuran / 3 h / 20 °C

6.2: 96 percent / aq. NaOH; aq. H₂O₂ / tetrahydrofuran / 0.5 h / 0 °C

7.1: 75 percent / diisopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 3 h / 20 °C

With dmap; N-Bromosuccinimide; 9-borabicyclo[3.3.1]nonane dimer; n-butyllithium; di-isopropyl azodicarboxylate; potassium hydride; triethylamine; triphenylphosphine; In tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide; 7.1: Mitsunobu coupling;
DOI:10.1016/j.tet.2007.04.031