Technology Process of 5-((16R,17R)-16-methoxy-17-methylpentatriacontane-1-sulfonyl)-1-phenyl-1H-triazole
There total 24 articles about 5-((16R,17R)-16-methoxy-17-methylpentatriacontane-1-sulfonyl)-1-phenyl-1H-triazole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
ammonium molybdate tetrahydrate; dihydrogen peroxide;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
DOI:10.1016/j.tet.2007.01.007
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 90 percent / potassium carbonate / acetone / 16 h / 20 °C
2: 89 percent / ammonium molybdate(VI) tetrahydrate; aq. hydrogen peroxide / tetrahydrofuran; various solvent(s) / 2 h / 20 °C
3: 91 percent / lithium hexamethyldisilazide / tetrahydrofuran / 16 h / 20 °C
4: 93 percent / hydrogen / palladium on charcoal / ethanol
5: 98 percent / potassium hydroxide / methanol; tetrahydrofuran / 3 h / 40 °C
6: 85 percent / N-bromosuccinimide; triphenylphosphine / CH2Cl2 / 1 h / 20 °C
7: 91 percent / potassium carbonate / acetone / 18 h / 20 °C
8: 82 percent / ammonium heptamolybdate(VI) tetrahydrate; aq. hydrogen peroxide / tetrahydrofuran; various solvent(s) / 1 h / 20 °C
With
potassium hydroxide; N-Bromosuccinimide; ammonium molybdate tetrahydrate; ammonium molybdate tetrahydrate; hydrogen; dihydrogen peroxide; potassium carbonate; triphenylphosphine; lithium hexamethyldisilazane;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; acetone;
3: Julia-Kocienski reaction;
DOI:10.1016/j.tet.2007.01.007
- Guidance literature:
-
Multi-step reaction with 10 steps
1.1: magnesium / tetrahydrofuran / 2 h / Heating
1.2: 75 percent / copper iodide / tetrahydrofuran / 3 h / -30 °C
2.1: 94 percent / sodium hydride / tetrahydrofuran; various solvent(s) / 16 h / 20 °C
3.1: 81 percent / p-toluenesulfonic acid monohydrate / tetrahydrofuran; methanol; H2O / 0.5 h / Heating
4.1: 87 percent / pyridinium chlorochromate / CH2Cl2 / 0.75 h / Heating
5.1: 91 percent / lithium hexamethyldisilazide / tetrahydrofuran / 16 h / 20 °C
6.1: 93 percent / hydrogen / palladium on charcoal / ethanol
7.1: 98 percent / potassium hydroxide / methanol; tetrahydrofuran / 3 h / 40 °C
8.1: 85 percent / N-bromosuccinimide; triphenylphosphine / CH2Cl2 / 1 h / 20 °C
9.1: 91 percent / potassium carbonate / acetone / 18 h / 20 °C
10.1: 82 percent / ammonium heptamolybdate(VI) tetrahydrate; aq. hydrogen peroxide / tetrahydrofuran; various solvent(s) / 1 h / 20 °C
With
potassium hydroxide; N-Bromosuccinimide; ammonium molybdate tetrahydrate; hydrogen; dihydrogen peroxide; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; magnesium; triphenylphosphine; pyridinium chlorochromate; lithium hexamethyldisilazane;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water; acetone;
5.1: Julia-Kocienski reaction;
DOI:10.1016/j.tet.2007.01.007
