methyl 2-carbamoyl-5-dimethylamino-5-phenylpentane-2,4-dienoate

Base Information

• Chemical Name: methyl 2-carbamoyl-5-dimethylamino-5-phenylpentane-2,4-dienoate
• CAS No.: 1202163-24-3
• Molecular Formula: C₁₅H₁₈N₂O₃
• Molecular Weight: 274.32
• Mol file: 1202163-24-3.mol

Synonyms:methyl 2-carbamoyl-5-dimethylamino-5-phenylpentane-2,4-dienoate

Chemical Property of methyl 2-carbamoyl-5-dimethylamino-5-phenylpentane-2,4-dienoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-carbamoyl-5-dimethylamino-5-phenylpentane-2,4-dienoate

There total 1 articles about methyl 2-carbamoyl-5-dimethylamino-5-phenylpentane-2,4-dienoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

methanol (67-56-1) + 1-phenyl-3-dimethylaminoprop-2-enone (1201-93-0) + cyanoacetic acid amide (107-91-5) → methyl 2-carbamoyl-5-dimethylamino-5-phenylpentane-2,4-dienoate (1202163-24-3)

Guidance literature:

Reflux;

Reference yield: 66.0%

methyl 2-carbamoyl-5-dimethylamino-5-phenylpentane-2,4-dienoate (1202163-24-3) → Methyl 1,2-Dihydro-2-oxo-6-phenyl-3-pyridinecarboxylate (125031-47-2)

Guidance literature:

With acetic acid; In toluene; Reflux;

Reference yield:

methyl 2-carbamoyl-5-dimethylamino-5-phenylpentane-2,4-dienoate (1202163-24-3) → methyl 2-phenylthio-6-phenyl-pyridine-3-carboxylate (1202163-51-6)

Guidance literature:

Multi-step reaction with 3 steps

1: acetic acid / toluene / Reflux

2: trichlorophosphate / N,N-dimethyl-formamide / 16 h / Reflux

3: potassium carbonate / acetonitrile / Reflux

With potassium carbonate; acetic acid; trichlorophosphate; N,N-dimethyl-formamide; In toluene; acetonitrile;

upstream raw materials:

methanol

1-phenyl-3-dimethylaminoprop-2-enone

cyanoacetic acid amide

Downstream raw materials:

Methyl 1,2-Dihydro-2-oxo-6-phenyl-3-pyridinecarboxylate

2-chloro-6-phenylpyridine-3-carboxylic acid methyl ester

methyl 2-(piperidin-1-yl)-6-phenyl-pyridine-3-carboxylate

methyl 2-phenylthio-6-phenyl-pyridine-3-carboxylate